BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 七月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在危险因素
  • 骨痛
  • 原发灶治疗后出现可触及的肿物
  • 胸膜腔积液

其他诊断因素

  • 呼吸短促
  • 厌食
  • 体重减轻
  • 神经性疼痛或无力、头痛、癫痫发作

危险因素

  • 女性
  • 50 岁以上
  • 乳腺癌和/或卵巢癌家族史
  • 双亲存在 BRCA1(1 型乳腺癌,早发型)或 BRCA2(2 型乳腺癌易感蛋白)突变

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 肝功能检查 (LFT)
  • 胸部 X 线检查 (CXR)
全部具体信息

需要考虑的检查

  • 磁共振(针对关注的部位,例如骨骼、脑部)
  • PET 扫描
  • 转移灶活检
  • 多门控捕获 (MUGA) 扫描
全部具体信息

治疗流程

贡献者

Edward Sauter MD, PhD

Director

Breast Surgery Program

Hartford Healthcare

Hartford

Visiting Professor of Surgery

University of Connecticut School of Medicine

Farmington

CT

利益冲突披露
ES declares that he has no competing interests.

Hematology and Oncology

Ellis Fischel Cancer Center

Margaret Proctor Mulligan Assistant Professor of Clinical Medicine

Medical Oncology - Breast Program Director

University of Missouri

Columbia

MO

利益冲突披露
PN declares that she has no competing interests.

Professor

Clinical Medicine

University of Missouri

Columbia

MO

利益冲突披露
Not disclosed.

Dr Edward Sauter, Dr Puja Nistala, and Dr Donald Doll would like to gratefully acknowledge Dr Carl E. Freter and Dr Michael Perry, the previous contributors to this monograph.

利益冲突披露
CEF and MP declare that they have no competing interests.

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Professor

Assistant Dean

Undergraduate Program

McMaster University

Hamilton

Ontario

Canada

利益冲突披露
AN declares that he has no competing interests.

Consultant

Honorary Senior Lecturer in Medical Oncology

South West Wales Cancer Centre

Swansea

UK

利益冲突披露
GB has received honoraria for participation in advisory boards (AstraZeneca, Novartis, Pfizer, Roche, GSK, Cephalon, Amgen, Sanofi, Aventis), speaker's fees (AstraZeneca, Novartis, Sanofi, Aventis), and hospitality at conferences (AstraZeneca, Novartis, Pfizer, Roche, Aventis).

Assistant Professor

Division of Hematology/Oncology

Department of Medicine

University of Alabama at Birmingham

Birmingham

AL

利益冲突披露
CV declares that University of Alabama at Birmingham has received research support from Pfizer, F. Hoffmann-La Roche, and Incyte.

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