BMJ Best Practice
最后审核时间: 六月 2019
最近更新时间: 三月 2019

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 发热或体温低
  • 呼吸急促
  • 心动过速

其他诊断因素

  • 低血压
  • 反映基础病变特定的局灶性体征和症状

危险因素

  • 免疫缺陷
  • 合并症
  • 较小的年龄(尤其是新生儿)
  • 围产期感染危险因素(新生儿)

诊断性检查

首要检查

  • FBC 和分类计数
  • 血清葡萄糖
  • 血液培养
  • 尿液分析
全部具体信息

需要考虑的检查

  • 腰椎穿刺:
  • 脑膜炎球菌聚合酶链反应分析
  • 支气管肺泡灌洗培养
  • 单纯疱疹病毒 (HSV) 聚合酶链反应(血液和脑脊液)
全部具体信息

新兴检查

  • 血清原降钙素
  • 新出现的生物标志物
  • PhenoTest™ BC 试剂盒
全部具体信息

治疗流程

贡献者

Director

Paediatric Intensive Care Unit

King’s College Hospital

London

UK

利益冲突披露
AD declares that he has no competing interests.

Dr Akash Deep would like to gratefully acknowledge Dr Jeremy Tong and Dr Adrian Plunkett, previous contributors to this topic. JT and AP are authors involved in the Paediatric Sepsis Six initiative, cited in this topic.

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Professor of Paediatric Immunology & Infectious Diseases

Director, NIHR Wellcome Trust Clinical Research Facility

University of Southampton

Southampton

UK

利益冲突披露
SNF declares that he has no competing interests.

Assistant Professor

Texas Children's Hospital and Baylor College of Medicine

Houston

TX

利益冲突披露
MP declares that he has no competing interests.

Faculty, Pediatric Critical Care Medicine

Seattle Children's Hospital

University of Washington School of Medicine

Seattle

WA

利益冲突披露
JJZ receives research grant support from NIH/NICHD and ImmuneXpress; travel reimbursement from the Society of Critical Care Medicine to attend board meetings; and royalties from Elsevier for action as a co-editor for the textbook Pediatric Critical Care.

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