Atypical presentations of superficial vein thrombophlebitis (SVT) include infected SVT, migratory thrombophlebitis, and Mondor's disease. Infected SVT can present with purulent discharge (suppurative thrombophlebitis) or without purulent discharge (non-suppurative thrombophlebitis). It is usually a complication of a skin infection (such as cellulitis); intravenous cannulation or chemical injection of the vein; or intravenous drug use. Migratory thrombophlebitis is defined by repeated thromboses developing in superficial veins, at varying sites but most commonly in the leg. It is usually associated with malignancy, particularly pancreatic adenocarcinoma. It can also be seen with Behcet's and Buerger's disease. Mondor's disease describes thrombophlebitis of a superficial vein in the subcutaneous fat of the breast and anterior chest wall, usually in women, and it may be associated with underlying malignancy. It also includes thrombophlebitis of the dorsal vein of the penis, generally caused by trauma or repetitive injury.
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