Superficial vein thrombophlebitis (SVT) is thought to be a relatively common condition, but its exact incidence remains to be determined. This is in part due to the lack of studies in a disease thought to be relatively benign and self-limiting. Nonetheless, its incidence is generally thought to be higher than that of deep vein thrombosis, which has an estimated frequency of 1 in 1000 persons a year.[1]Anderson FA Jr., Wheeler HB, Goldberg RJ, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism: the Worcester DVT Study. Arch Intern Med. 1991 May;151(5):933-8.http://www.ncbi.nlm.nih.gov/pubmed/2025141?tool=bestpractice.com[2]Hanson JN, Ascher E, DePippo P, et al. Saphenous vein thrombophlebitis (SVT): a deceptively benign disease. J Vasc Surg. 1998 Apr;27(4):677-80.http://www.ncbi.nlm.nih.gov/pubmed/9576081?tool=bestpractice.com[3]Nordstrom M, Lindblad B, Bergqvist D, et al. A prospective study of the incidence of deep-vein thrombosis within a defined urban population. J Intern Med. 1992 Aug;232(2):155-60.http://www.ncbi.nlm.nih.gov/pubmed/1506812?tool=bestpractice.com[4]Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev. 2018 Feb 25;(2):CD004982.http://cochranelibrary-wiley.com/doi/10.1002/14651858.CD004982.pub6/fullhttp://www.ncbi.nlm.nih.gov/pubmed/29478266?tool=bestpractice.com Some reports estimate an incidence of anywhere between 3% to 11% of the general population.[5]Widmer LK, Stahelin HB, Nissen C, et al. Venen-, Arterien-krankheiten, koronare Herzkrankheit bei Berufstatigen: Prospektivepidemiologische Untersuchung. Basler studie I-III, 1959-1978. Bern, Switzerland: Huber; 1981. 大多数研究报告中指出,相比男性,女性发病率高出4~6倍,可能与女性中静脉曲张患病率增高有关。[6]Unno N, Mitsuoka H, Uchiyama T, et al. Superficial thrombophlebitis of the lower limbs in patients with varicose veins. Surg Today. 2002;32(5):397-401.http://www.ncbi.nlm.nih.gov/pubmed/12061687?tool=bestpractice.com[7]Lofgren EP, Lofgren KA. The surgical treatment of superficial thrombophlebitis. Surgery. 1981 Jul;90(1):49-54.http://www.ncbi.nlm.nih.gov/pubmed/7245050?tool=bestpractice.com[8]Belcaro G, Nicolaides AN, Errichi BM, et al. Superficial thrombophlebitis of the legs: a randomized, controlled, follow-up study. Angiology. 1999 Jul;50(7):523-9.http://www.ncbi.nlm.nih.gov/pubmed/10431991?tool=bestpractice.com[9]Decousus H, Epinat M, Guillot K, et al. Superficial vein thrombosis: risk factors, diagnosis and treatment. Curr Opin Pulm Med. 2003 Sep;9(5):393-7.http://www.ncbi.nlm.nih.gov/pubmed/12904709?tool=bestpractice.com[10]Zollinger RW, Williams RD, Briggs DO. Problems in the diagnosis and treatment of thrombophlebitis. Arch Surg. 1962;85:34-40.[11]Husni EA, Williams WA. Superficial thrombophlebitis of lower limbs. Surgery. 1982 Jan;91(1):70-4.http://www.ncbi.nlm.nih.gov/pubmed/7054911?tool=bestpractice.com[12]Decousus H, Quéré I, Presles E, et al. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. Ann Intern Med. 2010 Feb 16;152(4):218-24.http://www.ncbi.nlm.nih.gov/pubmed/20157136?tool=bestpractice.com[13]Nasr H, Scriven JM. Superficial thrombophlebitis (superficial venous thrombosis). BMJ. 2015 Jun 22;350:h2039.http://www.ncbi.nlm.nih.gov/pubmed/26099257?tool=bestpractice.com