罗伊氏乳杆菌
罗伊氏乳杆菌是一种益生菌。已经证明一些肠绞痛婴儿的肠道乳酸杆菌数量较少。[29]Savino F, Cresi F, Pautasso S, et al. Intestinal microflora in breastfed colicky and non-colicky infants. Acta Paediatr. 2004;93:825-829.http://www.ncbi.nlm.nih.gov/pubmed/15244234?tool=bestpractice.com[30]Savino F, Bailo E, Oggero R, et al. Bacterial counts of intestinal Lactobacillus species in infants with colic. Pediatr Allergy Immunol. 2005;16:72-75.http://www.ncbi.nlm.nih.gov/pubmed/15693915?tool=bestpractice.com据推测,罗伊氏乳杆菌有助于将肠道生态平衡从潜在的有害菌群转变为有益菌群,从而减少胃肠道感染和过敏性疾病的风险。[31]Neu J, Caicedo R. Probiotics: protecting the intestinal ecosystem? J Pediatr. 2005;147:143-146.http://www.ncbi.nlm.nih.gov/pubmed/16126038?tool=bestpractice.com[32]Weizman Z, Asli G, Alsheikh A. Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents. Pediatrics. 2005;115:5-9.http://www.ncbi.nlm.nih.gov/pubmed/15629974?tool=bestpractice.com一些研究已经证明症状可得到一些改善。[33]Savino F, Cordisco L, Tarasco V, et al. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. Pediatrics. 2010;126:e526-e533.http://www.ncbi.nlm.nih.gov/pubmed/20713478?tool=bestpractice.com[34]Savino F, Pelle E, Palumeri E, et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study. Pediatrics. 2007;119:e124-e130.http://www.ncbi.nlm.nih.gov/pubmed/17200238?tool=bestpractice.com[35]Szajewska H, Gyrczuk E, Horvath A. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2013;162:257-262.http://www.ncbi.nlm.nih.gov/pubmed/22981952?tool=bestpractice.com[36]Sung V, Collett S, de Gooyer T, et al. Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis. JAMA Pediatr. 2013;167:1150-1157.http://www.ncbi.nlm.nih.gov/pubmed/24100440?tool=bestpractice.com[37]Indrio F, Di Mauro A, Riezzo G, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168:228-233.http://archpedi.jamanetwork.com/article.aspx?articleid=1812293http://www.ncbi.nlm.nih.gov/pubmed/24424513?tool=bestpractice.com[38]Sung V, Hiscock H, Tang ML, et al. Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial. BMJ. 2014;348:g2107.http://www.bmj.com/content/348/bmj.g2107.longhttp://www.ncbi.nlm.nih.gov/pubmed/24690625?tool=bestpractice.com[39]Chau K, Lau E, Greenberg S, et al. Probiotics for infantile colic: a randomized, double-blind, placebo-controlled trial investigating Lactobacillus reuteri DSM 17938. J Pediatr. 2015;166:74-78.http://www.jpeds.com/article/S0022-3476(14)00848-8/fulltexthttp://www.ncbi.nlm.nih.gov/pubmed/25444531?tool=bestpractice.com