坏死性筋膜炎

合理使用手术联合抗生素进行治疗的坏死性筋膜炎的病死率估计在 10% 至 40% 之间。 发生休克和终末器官损伤的患者死亡率较高，接近 50% 至 70%。[5]Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.https://academic.oup.com/cid/article/59/2/e10/2895845 坏死性筋膜炎的复发较为罕见。[4]Pasternack MS, Swartz MN. Cellulitis, necrotizing fasciitis, and subcutaneous tissue infections. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Philadelphia, PA: Elsevier; 2015:1194-215.[5]Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.https://academic.oup.com/cid/article/59/2/e10/2895845 然而，显著的功能性和美观性病症可能会在手术治疗后早期出现，这可能需要后续重建或修复。