治疗疗效:有中等证据表明,生长抑素类似物可帮助控制症状。[19]Oberg K. Chemotherapy and biotherapy in the treatment of neuroendocrine tumours. Ann Oncol. 2001;12 Suppl 2:S111-4.http://www.ncbi.nlm.nih.gov/pubmed/11762335?tool=bestpractice.com[20]Maton PN, Gardner JD, Jensen RT. Use of long-acting somatostatin analog SMS 201-995 in patients with pancreatic islet cell tumors. Dig Dis Sci. 1989;34(3 suppl):28-39S.http://www.ncbi.nlm.nih.gov/pubmed/2537716?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
治疗疗效:有中等证据表明,生长抑素类似物可帮助控制症状。[19]Oberg K. Chemotherapy and biotherapy in the treatment of neuroendocrine tumours. Ann Oncol. 2001;12 Suppl 2:S111-4.http://www.ncbi.nlm.nih.gov/pubmed/11762335?tool=bestpractice.com[20]Maton PN, Gardner JD, Jensen RT. Use of long-acting somatostatin analog SMS 201-995 in patients with pancreatic islet cell tumors. Dig Dis Sci. 1989;34(3 suppl):28-39S.http://www.ncbi.nlm.nih.gov/pubmed/2537716?tool=bestpractice.com
治疗疗效:有中等证据表明,肝脏定向治疗适用于不能手术切除的肝脏转移患者。[26]Ho AS, Picus J, Darcy MD, et al. Long-term outcome after chemoembolization and embolization of hepatic metastatic lesions from neuroendocrine tumors. AJR Am J Roentgenol. 2007 May;188(5):1201-7.http://www.ajronline.org/doi/pdf/10.2214/AJR.06.0933http://www.ncbi.nlm.nih.gov/pubmed/17449759?tool=bestpractice.com[27]King J, Quinn R, Glenn DM, et al. Radioembolization with selective internal radiation microspheres for neuroendocrine liver metastases. Cancer. 2008 Sep 1;113(5):921-9.http://www.ncbi.nlm.nih.gov/pubmed/18618495?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
治疗疗效:有中等证据表明,肝脏定向治疗适用于不能手术切除的肝脏转移患者。[26]Ho AS, Picus J, Darcy MD, et al. Long-term outcome after chemoembolization and embolization of hepatic metastatic lesions from neuroendocrine tumors. AJR Am J Roentgenol. 2007 May;188(5):1201-7.http://www.ajronline.org/doi/pdf/10.2214/AJR.06.0933http://www.ncbi.nlm.nih.gov/pubmed/17449759?tool=bestpractice.com[27]King J, Quinn R, Glenn DM, et al. Radioembolization with selective internal radiation microspheres for neuroendocrine liver metastases. Cancer. 2008 Sep 1;113(5):921-9.http://www.ncbi.nlm.nih.gov/pubmed/18618495?tool=bestpractice.com
治疗疗效:有中等证据表明,肝移植术在胰腺神经内分泌肿瘤且有肝转移的患者,可改善长期生存状况。[29]Máthé Z, Tagkalos E, Paul A, et al. Liver transplantation for hepatic metastases of neuroendocrine pancreatic tumors: a survival-based analysis. Transplantation. 2011 Mar 15;91(5):575-82.http://www.ncbi.nlm.nih.gov/pubmed/21200365?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
治疗疗效:有中等证据表明,肝移植术在胰腺神经内分泌肿瘤且有肝转移的患者,可改善长期生存状况。[29]Máthé Z, Tagkalos E, Paul A, et al. Liver transplantation for hepatic metastases of neuroendocrine pancreatic tumors: a survival-based analysis. Transplantation. 2011 Mar 15;91(5):575-82.http://www.ncbi.nlm.nih.gov/pubmed/21200365?tool=bestpractice.com