轻度疾病的自然病程可以是良性并采用医疗干预控制。有限的中度疾病需要更为积极的内科治疗并可能采取手术治疗以达到足够控制。控制差的中度疾病可发展为更为严重的疾病。仅凭内科治疗不可能完全缓解症状。应注意评估系统性感染的证据。对于中重度疾病,建议咨询整形外科。长期重度疾病可导致淋巴水肿和鳞状细胞癌发展。可严重影响患者生活质量。[38]Revuz JE, Canoui-Poitrine F, Wolkenstein P, et al. Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol. 2008;59:596-601.http://www.ncbi.nlm.nih.gov/pubmed/18674845?tool=bestpractice.com[39]Wolkenstein P, Loundou A, Barrau K, et al; Quality of Life Group of the French Society of Dermatology. Quality of life impairment in hidradenitis suppurativa: a study of 61 cases. J Am Acad Dermatol. 2007;56:621-623.http://www.ncbi.nlm.nih.gov/pubmed/17097366?tool=bestpractice.com