在美国,脑膜瘤占原发性颅内肿瘤的36.1%。[1]Ostrom QT, Gittleman H, Farah P, et al. CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010. Neuro Oncol. 2013;15(suppl 2):ii1-ii56. [Erratum in: Neuro Oncol. 2014;16:760.]http://neuro-oncology.oxfordjournals.org/content/15/suppl_2/ii1.longhttp://www.ncbi.nlm.nih.gov/pubmed/24137015?tool=bestpractice.com女性多发,占男性原发性颅内肿瘤的20%,女性的38%。[4]Claus EB, Bondy ML, Schildkraut JM, et al. Epidemiology of intracranial meningioma. Neurosurgery. 2005;57:1088-1095.http://www.ncbi.nlm.nih.gov/pubmed/16331155?tool=bestpractice.com[5]Longstreth WT, Jr, Dennis LK, McGuire VM, et al. Epidemiology of intracranial meningioma. Cancer. 1993;72:639-648.http://onlinelibrary.wiley.com/doi/10.1002/1097-0142(19930801)72:3%3C639::AID-CNCR2820720304%3E3.0.CO;2-P/pdfhttp://www.ncbi.nlm.nih.gov/pubmed/8334619?tool=bestpractice.com根据美国脑肿瘤登记中心(CBTRUS)的数据,经年龄校准后男女发病率比为4.55:10.26(每10万人)。[1]Ostrom QT, Gittleman H, Farah P, et al. CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010. Neuro Oncol. 2013;15(suppl 2):ii1-ii56. [Erratum in: Neuro Oncol. 2014;16:760.]http://neuro-oncology.oxfordjournals.org/content/15/suppl_2/ii1.longhttp://www.ncbi.nlm.nih.gov/pubmed/24137015?tool=bestpractice.com黑色人种的年龄发病率(9.14)比白色人种(7.40)和亚洲人(4.78)稍高。脑膜瘤在两性中的发病率都随年龄增加。在35岁以上的成人中脑膜瘤为最为常见的颅内原发性肿瘤。[1]Ostrom QT, Gittleman H, Farah P, et al. CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010. Neuro Oncol. 2013;15(suppl 2):ii1-ii56. [Erratum in: Neuro Oncol. 2014;16:760.]http://neuro-oncology.oxfordjournals.org/content/15/suppl_2/ii1.longhttp://www.ncbi.nlm.nih.gov/pubmed/24137015?tool=bestpractice.com在美国每年有大约25000例的新患者诊断为脑膜瘤。在英国,对于百万女性的研究提示脑膜瘤的发病率随着体重和体质指数的增加而增加。[6]Benson VS, Pirie K, Green J, et al. Lifestyle factors and primary glioma and meningioma tumours in the Million Women Study cohort. Br J Cancer. 2008;99:185-190.http://www.nature.com/bjc/journal/v99/n1/full/6604445a.htmlhttp://www.ncbi.nlm.nih.gov/pubmed/18560401?tool=bestpractice.com复发性脑膜瘤的治疗选择有限。