臭虫叮咬的局部性反应是自限性的,通常持续几天至几周。[27]Ter Poorten MC, Prose NS. The return of the common bedbug. Pediatr Dermatol. 2005;22:183-187.http://www.ncbi.nlm.nih.gov/pubmed/15916561?tool=bestpractice.com病变是否复发取决于生活环境中的侵染是否被清除。当个体患者反复被叮咬时,更可能发生强烈的反应。[17]Krause-Parello CA, Sciscione P. Bedbugs: an equal opportunist and cosmopolitan creature. J Sch Nurs. 2009;25:126-132.http://www.ncbi.nlm.nih.gov/pubmed/19233933?tool=bestpractice.com[28]Fletcher CL, Ardern-Jones MR, Hay RJ. Widespread bullous eruption due to multiple bed bug bites. Clin Exp Dermatol. 2002;27:74-75.http://www.ncbi.nlm.nih.gov/pubmed/11952681?tool=bestpractice.com