在英国,接受常规宫颈筛查的 16-25 岁女性中,识别出人乳头瘤病毒 (human papillomavirus, HPV) 感染的患病率估计为 42%。[8]Cuschieri KS, Cubie HA, Whitley MW, et al. Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening population. J Clin Pathol. 2004 Jan;57(1):68-72.https://jcp.bmj.com/content/57/1/68.longhttp://www.ncbi.nlm.nih.gov/pubmed/14693839?tool=bestpractice.com 这一比率随年龄的增大而升高。[8]Cuschieri KS, Cubie HA, Whitley MW, et al. Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening population. J Clin Pathol. 2004 Jan;57(1):68-72.https://jcp.bmj.com/content/57/1/68.longhttp://www.ncbi.nlm.nih.gov/pubmed/14693839?tool=bestpractice.com
对于 18-59 岁的美国成人,在 2013-2014 年期间,任何生殖器 HPV 感染的患病率均为 42.5%(男性:45.2%;女性:39.9%)。[9]McQuillan G, Kruszon-Moran D, Markowitz LE, et al. Prevalence of HPV in adults aged 18-69: United States, 2011-2014. NCHS Data Brief. 2017 Apr;(280):1-8.http://www.ncbi.nlm.nih.gov/pubmed/28437239?tool=bestpractice.com 同期,在 18-59 岁的成人中,高风险 HPV 感染的患病率为 22.7%(男性:25.1%;女性:20.4%)。非西班牙裔黑人男性的高风险生殖器 HPV 感染的患病率最高 (40.3 %)。[9]McQuillan G, Kruszon-Moran D, Markowitz LE, et al. Prevalence of HPV in adults aged 18-69: United States, 2011-2014. NCHS Data Brief. 2017 Apr;(280):1-8.http://www.ncbi.nlm.nih.gov/pubmed/28437239?tool=bestpractice.com 拉丁美洲的 HPV 感染患病率在全世界是最高的。[10]Perez G, Lazcano-Ponce E, Hernandez-Avila M, et al. Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like-particle vaccine in Latin American women. Int J Cancer. 2008 Mar 15;122(6):1311-8.http://www.ncbi.nlm.nih.gov/pubmed/18000825?tool=bestpractice.com