维生素 C
辅助使用维生素 C 在降低远端桡骨骨折后复杂区域疼痛综合征的患病率方面可能带来一些获益,但近期文献对此提出了质疑。 不管怎样,骨折后给予维生素 C 连续治疗 50 天与患病风险低有关。[34]Zollinger PE, Tuinebreijer WE, Breederveld RS, et al. Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response study. J Bone Joint Surg Am. 2007;89:1424-1431.http://www.ncbi.nlm.nih.gov/pubmed/17606778?tool=bestpractice.com[35]Ekrol I, Duckworth AD, Ralston SH, et al. The influence of vitamin C on the outcome of distal radial fractures: a double-blind, randomized controlled trial. J Bone Joint Surg Am. 2014;96:1451-1459.http://www.ncbi.nlm.nih.gov/pubmed/25187584?tool=bestpractice.com