经叶酸和抗生素治疗后,可预期完全缓解。在治疗开始后的 2 日至 1 周内,治疗反应通常迅速,伴症状性、实验室和病理学改善。[34]Klipstein FA. Absorption of physiologic doses of folic acid in subjects with tropical sprue responding to tetracycline therapy. Blood. 1969;34:191-203.http://www.bloodjournal.org/content/bloodjournal/34/2/191.full.pdf?sso-checked=truehttp://www.ncbi.nlm.nih.gov/pubmed/5798456?tool=bestpractice.com从疾病流行区返回且接受 6 个月至 1 年治疗的旅行者复发的情况罕见。疾病流行区本地患者高达 50% 在治疗后会复发。[35]Rickles FR, Klipstein FA, Tomasini J, et al. Long-term follow-up of antibiotic-treated tropical sprue. Ann Intern Med. 1972;76:203-210.http://www.ncbi.nlm.nih.gov/pubmed/5009590?tool=bestpractice.com[36]Guerra R, Wheby MS, Bayless TM. Long term antibiotic in tropical sprue. Ann Intern Med. 1965;63:619-634.http://www.ncbi.nlm.nih.gov/pubmed/5838328?tool=bestpractice.com[37]Ramakrishna BS, Venkataraman S, Mukhopadhya A. Tropical malabsorption. Postgrad Med J. 2006;82:779-787.http://www.ncbi.nlm.nih.gov/pubmed/17148698?tool=bestpractice.com