关于银屑病的发病率缺乏可靠的数据。 [2]World Health Organization. Global report on psoriasis. 2016 [internet publication].http://apps.who.int/iris/handle/10665/204417各国发布的银屑病流行病学数据各不相同,研究报告的患病率在 0.09% 和 11.40% 之间。[3]Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. 1996 Sep;35(9):633-9.http://www.ncbi.nlm.nih.gov/pubmed/8876289?tool=bestpractice.com[4]Danielsen K, Olsen AO, Wilsgaard T, et al. Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort. Br J Dermatol. 2013 Jun;168(6):1303-10.http://www.ncbi.nlm.nih.gov/pubmed/23374051?tool=bestpractice.com在大多数发达国家,患病率在 1.5% 至 5.0% 之间; [5]Parisi R, Symmons DPM, Griffiths CEM, et al. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2013;133(2):377–85. http://www.ncbi.nlm.nih.gov/pubmed/23014338?tool=bestpractice.com有证据表明这些地区的患病率正在增加。[6]Danielsen K, Olsen AO, Wilsgaard T, et al. Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort. Br J Dermatol. 2013 Jun;168(6):1303-10.http://www.ncbi.nlm.nih.gov/pubmed/23374051?tool=bestpractice.com平均发病年龄为 28 岁,男女分布均等。[7]Gelfand JM, Stern RS, Nijsten T, et al. The prevalence of psoriasis in African Americans: results from a population-based. J Am Acad Dermatol. 2005 Jan;52(1):23-6.http://www.ncbi.nlm.nih.gov/pubmed/15627076?tool=bestpractice.com
在银屑病患者中,银屑病关节炎患病率因研究设计不同而存在广泛差异。一项针对欧洲和北美皮肤病学门诊患者的研究显示,银屑病关节炎的患病率为 30%,[8]Mease PJ, Gladman DD, Papp KA, et al. Prevalence of rheumatologist-diagnosed psoriatic arthritis in patients with psoriasis in European/North American dermatology clinics. J Am Acad Dermatol. 2013 Nov;69(5):729-35.http://www.ncbi.nlm.nih.gov/pubmed/23981683?tool=bestpractice.com 美国明尼苏达州一项针对 1633 名患者的社区研究发现,银屑病关节炎 20 年累积发病率为 7.5%。[9]Wilson FC, Icen M, Crowson CS, et al. Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: a population-based study. Arthritis Rheum. 2009 Feb 15;61(2):233-9.http://onlinelibrary.wiley.com/doi/10.1002/art.24172/fullhttp://www.ncbi.nlm.nih.gov/pubmed/19177544?tool=bestpractice.com