妊娠胆汁淤积症

Eloranta ML, Hakli T, Hiltunen M, et al. Association of single nucleotide polymorphisms of the bile salt sport pump gene with intrahepatic cholestasis of pregnancy. Scand J Gastroenterol. 2003 Jun;38(6):648-52.

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Dixon PH, Weerasekera N, Linton KJ, et al. Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet. 2000 May 1;9(8):1209-17.

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European Association for the Study of the Liver. Clinical practice guidelines: management of cholestatic liver diseases. J Hepatol. 2009 Aug;51(2):237-67.

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Glantz A, Marschall HU, Lammert F, et al. Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology. 2005;42:1399-1405.

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Bacq Y, Sentilhes L, Reyes HB, et al. Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis. Gastroenterology. 2012 Dec;143(6):1492-501.

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Fisk NM, Bye WB, Storey GN. Maternal features of obstetric cholestasis: 20 years experience at King George V Hospital. Aust N Z J Obstet Gynaecol. 1988 Aug;28(3):172-6.

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Heinonen S, Kirkinen P. Pregnancy outcome with intrahepatic cholestasis. Obstet Gynecol. 1999 Aug;94(2):189-93.

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1.  Lammert F, Marschall HU, Glantz A, et al. Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management. J Hepatol. 200;33:1012-1021.

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2.  Kenyon AP, Piercy CN, Girling J, et al. Obstetric cholestasis, outcome with active management: a series of 70 cases. BJOG. 2002;109:282-288.

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3.  Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: relationships between bile acid levels and fetal complication rates. Hepatology. 2004 Aug;40(2):467-74.

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4.  Royal College of Obstetrics and Gynaecologists. Obstetric cholestasis. Green-top guideline 43. April 2011. [internet publication].

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5.  Reyes H, Simon F. Intrahepatic cholestasis of pregnancy: an estrogen-related disease. Semin Liver Dis. 1993 Aug;13(3):289-301.

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6.  Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function and regulation. Physiol Rev. 2003 Apr;83(2):633-71.

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7.  Rosmorduc O, Hermelin B, Boelle PY, et al. ABCB4 gene mutation-associated cholelithiasis in adults. Gastroenterology. 2003 Aug;125(2):452-9.

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8.  Milkiewicz P, Gallagher R, Chambers J, et al. Obstetric cholestasis with elevated gamma glutamyl transpeptidase: incidence, presentation and treatment. J Gastroenterol Hepatol. 2003 Nov;18(11):1283-6.

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9.  Eloranta ML, Hakli T, Hiltunen M, et al. Association of single nucleotide polymorphisms of the bile salt sport pump gene with intrahepatic cholestasis of pregnancy. Scand J Gastroenterol. 2003 Jun;38(6):648-52.

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10.  Savander M, Ropponen A, Avela K, et al. Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy. Gut. 2003 Jul;52(7):1025-9.

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11.  Kroumpouzos G, Cohen LM. Specific dermatoses of pregnancy: an evidence-based systematic review. Am J Obstet Gynecol. 2003 Apr;188(4):1083-92.

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12.  Dixon PH, Weerasekera N, Linton KJ, et al. Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet. 2000 May 1;9(8):1209-17.

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• 摘要

13.  European Association for the Study of the Liver. Clinical practice guidelines: management of cholestatic liver diseases. J Hepatol. 2009 Aug;51(2):237-67.

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14.  Howard PJ, Murphy GM. Bile acid stress in mother and baby unit. Eur J Gastroenterol Hepatol. 2003;15:317-321.

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15.  Germain AM, Kato S, Carvajal JA, et al. Bile acids increase response and expression of human myometrial oxytocin receptor. Am J Obstet Gynecol. 2003;189:577-582.

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16.  Monte MJ, Villanueva GR, Macias RI, et al. Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring. Clin Sci (Lond). 2003;105:347-353.

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17.  Reyes H, Sjovall J. Bile acids and progesterone metabolites in intrahepatic cholestasis of pregnancy. Ann Med. 2000;32:94-106.

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18.  Serrano MA, Macias RI, Vallejo M, et al. Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway. J Pharmacol Exp Ther. 2003;305:515-524.

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19.  Mottino AD, Veggi LM, Wood M, et al. Biliary secretion of glutathione in estradiol 17beta-D-glucuronide-induced cholestasis. J Pharmacol Exp Ther. 2003;307:306-313.

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20.  Saleh MM, Abdo KR. Intrahepatic cholestasis of pregnancy: review of the literature and evaluation of current evidence. J Womens Health (Larchmt). 2007 Jul-Aug;16(6):833-41.

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21.  Lopez J, Glasinovic JC, Marinovic I, et al. Clinical and laboratory characterization in 100 cases of pregnancy cholestasis. Rev Chil Obstet Ginecol. 1982;47(4):215-21.

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22.  Glantz A, Marschall HU, Lammert F, et al. Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology. 2005;42:1399-1405.

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23.  Locatelli A, Roncaglia N, Arreghini A, et al. Hepatitis C virus infection is associated with a higher incidence of cholestasis in pregnancy. Br J Obstet Gynaecol. 1999;106:498-500.

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24.  Warren JE, Blaylock RC, Silver RM. Plasmapheresis for the treatment of intrahepatic cholestasis of pregnancy refractory to medical treatment. Am J Obstet Gynecol. 2005;192:2088-2089.

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25.  Palma J, Reyes H, Ribalta J, et al. Ursodeoxycholic acid in treatment of cholestasis of pregnancy: a randomized, double blinded study controlled with placebo. J Hepatol. 1997 Dec;27(6):1022-8.

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26.  Bacq Y, Sentilhes L, Reyes HB, et al. Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis. Gastroenterology. 2012 Dec;143(6):1492-501.

• 摘要

27.  Fisk NM, Bye WB, Storey GN. Maternal features of obstetric cholestasis: 20 years experience at King George V Hospital. Aust N Z J Obstet Gynaecol. 1988 Aug;28(3):172-6.

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28.  Heinonen S, Kirkinen P. Pregnancy outcome with intrahepatic cholestasis. Obstet Gynecol. 1999 Aug;94(2):189-93.

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29.  Nicastri PL, Diaferia A, Tartagni M, et al. A randomized placebo-controlled trial of ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy. Br J Obstet Gynaecol. 1998 Nov;105(11):1205-7.

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30.  Binser T, Salaj P, Zima T, et al. Randomized prospective comparative study of ursodeoxycholic acid and S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis of pregnancy. J Perinat Med. 2006;34(5):383-91.

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