大多数持续性抑郁症患者在其一生中将出现一次或多次重性抑郁发作,还可能复发(“双重抑郁”)。[9]Kovacs M, Akiskal HS, Gatsonis C, et al. Childhood-onset dysthymic disorder. Clinical features and prospective naturalistic outcome. Arch Gen Psychiatry. 1994;51:365-374.http://www.ncbi.nlm.nih.gov/pubmed/8179460?tool=bestpractice.com[10]Klein DN, Nordern KA, Ferro T, et al. Thirty-month naturalistic follow-up study of early onset dysthymic disorder: course, diagnostic stability, and prediction of outcome. J Abnorm Psychol. 1998;107:338-348.http://www.ncbi.nlm.nih.gov/pubmed/9604563?tool=bestpractice.com[11]Klein DN, Schwartz JE, Rose S, et al. Five-year course and outcome of dysthymic disorder: a prospective, naturalistic follow-up study. Am J Psychiatry. 2000;157:931-939.http://www.ncbi.nlm.nih.gov/pubmed/10831473?tool=bestpractice.com
成人抑郁症
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