临床治愈率和微生物学成功率:高质量的证据表明,在治疗任何身体部位的医院相关性 MRSA 感染中,利奈唑胺和万古霉素的疗效并无显著差异。
系统评价或者受试者>200名的随机对照临床试验(RCT)。
临床治愈率和微生物学成功率:高质量的证据表明,在治疗任何身体部位的医院相关性 MRSA 感染中,利奈唑胺和万古霉素的疗效并无显著差异。
治愈率:中级证据表明,与联合应用抗生素相比,单独切开引流已足以治疗非复杂性皮肤脓肿。[21]Lee MC, Rios AM, Aten MF, et al. Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus. Pediatr Infect Dis J. 2004;23:123-127.http://www.ncbi.nlm.nih.gov/pubmed/14872177?tool=bestpractice.com[22]Rajendran PM, Young D, Maurer T, et al. Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother. 2007;51:4044-4048.http://aac.asm.org/cgi/content/full/51/11/4044http://www.ncbi.nlm.nih.gov/pubmed/17846141?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
治愈率:中级证据表明,与联合应用抗生素相比,单独切开引流已足以治疗非复杂性皮肤脓肿。[21]Lee MC, Rios AM, Aten MF, et al. Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus. Pediatr Infect Dis J. 2004;23:123-127.http://www.ncbi.nlm.nih.gov/pubmed/14872177?tool=bestpractice.com[22]Rajendran PM, Young D, Maurer T, et al. Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection. Antimicrob Agents Chemother. 2007;51:4044-4048.http://aac.asm.org/cgi/content/full/51/11/4044http://www.ncbi.nlm.nih.gov/pubmed/17846141?tool=bestpractice.com
死亡率:低质量证据表明,感染性心内膜炎合并心衰的患者,接受单独内科治疗的死亡率,高于接受内外科联合治疗者。[29]Moon MR, Stinson EB, Miller DC. Surgical treatment of endocarditis. Prog Cardiovasc Dis. 1997;40:239-264.http://www.ncbi.nlm.nih.gov/pubmed/9406678?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
死亡率:低质量证据表明,感染性心内膜炎合并心衰的患者,接受单独内科治疗的死亡率,高于接受内外科联合治疗者。[29]Moon MR, Stinson EB, Miller DC. Surgical treatment of endocarditis. Prog Cardiovasc Dis. 1997;40:239-264.http://www.ncbi.nlm.nih.gov/pubmed/9406678?tool=bestpractice.com