据报道美国RVO的发生率为0.7%,澳大利亚为1.6%。[1]Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1243-1247.http://www.ncbi.nlm.nih.gov/pubmed/9186446?tool=bestpractice.com[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com
CRVO常发生于大于65岁的老年人,男女发病率无差异。[1]Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1243-1247.http://www.ncbi.nlm.nih.gov/pubmed/9186446?tool=bestpractice.com[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com[3]Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol. 1994;117:429-441.http://www.ncbi.nlm.nih.gov/pubmed/8154523?tool=bestpractice.com[4]The Central Vein Occlusion Study Group. Baseline and early natural history report: the Central Vein Occlusion Study. Arch Ophthalmol. 1993;111:1087-1095.http://www.ncbi.nlm.nih.gov/pubmed/7688950?tool=bestpractice.com人群中CRVO发病率为0.1%-0.4%。[1]Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1243-1247.http://www.ncbi.nlm.nih.gov/pubmed/9186446?tool=bestpractice.com[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com在所有CRVO患者中,≥65岁者占71%。[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com
BRVO也常见于65岁以上的老人,无性别差异。[1]Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1243-1247.http://www.ncbi.nlm.nih.gov/pubmed/9186446?tool=bestpractice.com[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com人群中BRVO的发病率为0.6%-1.1%。[1]Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1243-1247.http://www.ncbi.nlm.nih.gov/pubmed/9186446?tool=bestpractice.com[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.comBRVO患者中≥65岁者占77%。[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com
Beaver Dam的研究报道,CRVO发病5年以上的人均发病率为0.002,15年以上的人均发病率为0.005。[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com[5]Klein R, Moss SE, Meuer SM, et al. The 15-year cumulative incidence of retinal vein occlusion: The Beaver Dam Eye Study. Arch Ophthalmol. 2008;126:513-518.http://www.ncbi.nlm.nih.gov/pubmed/18413521?tool=bestpractice.comBRVO的5年以上人均发病率为0.006,15年以上人均发病率为0.018。[2]Klein R, Klein BE, Moss SE, et al. The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study. Trans Am Ophthalmol Soc. 2000;98:133-141.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298220/pdf/taos00001-0142.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/11190017?tool=bestpractice.com[5]Klein R, Moss SE, Meuer SM, et al. The 15-year cumulative incidence of retinal vein occlusion: The Beaver Dam Eye Study. Arch Ophthalmol. 2008;126:513-518.http://www.ncbi.nlm.nih.gov/pubmed/18413521?tool=bestpractice.com
单眼CRVO患者对侧眼每年发生任一类型RVO的可能性约为1%,5年发生CRVO的可能性约为7%。[3]Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol. 1994;117:429-441.http://www.ncbi.nlm.nih.gov/pubmed/8154523?tool=bestpractice.com[6]The Central Vein Occlusion Study Group. Natural history and clinical management of central retinal vein occlusion. Arch Ophthalmol. 1997;115:486-491.http://www.ncbi.nlm.nih.gov/pubmed/9109757?tool=bestpractice.com[7]Hayreh SS. Central retinal vein occlusion. Ophthalmol Clin North Am. 1998;11:559-590.同样,单眼BRVO患者的对侧眼3年内发生任一类型RVO的可能性约为10%。