BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 一月 2018

小结

定义

病史和查体

其他诊断因素

  • 复发性感染病史
  • 疲劳
  • 脸色苍白
  • 出血或皮肤易出现瘀斑病史

危险因素

  • 药物或毒素暴露
  • 阵发性睡眠性血红蛋白尿 (PNH)
  • 近期肝炎
  • 妊娠

诊断性检查

首要检查

  • 全血细胞及分类
  • 网织红细胞计数
  • 骨髓活组织检查和细胞遗传学分析
全部具体信息

需要考虑的检查

  • 血清 B12 和叶酸水平
  • HIV 检测
  • 肝功能检测 (LFT)
  • 自身抗体筛查
全部具体信息

治疗流程

贡献者

Professor of Haematology

Consultant Haematologist

Department of Haematological Medicine

King's College Hospital NHS Foundation Trust

King’s College London

London

UK

利益冲突披露
JCWM has received fees for consulting for Novartis Global, Amgen, and GSK and has also consulted for Pfizer and Sanofi; received a fee for lectures given for Novartis and has also given lectures for Alexion and Sanofi; was awarded a research grant from Sanofi for King’s College London and has a research grant from GSK/Novartis awaiting final approval; and has received travel expenses from Novartis and Adienne to attend meetings.

Consultant Haematologist

Department of Haematological Medicine

King's College Hospital NHS Foundation Trust

London

UK

利益冲突披露
AGK is on the Speakers' Panel and Advisory Board for Novartis, Pfizer, Alexion, and Celgene. He is an author of a reference cited in the monograph.

Professor Marsh and Dr Kulasekararaj would like to gratefully acknowledge the assistance of Dr Ziyi Lim, Dr Philippe Armand, and Professor Joseph H. Antin, previous contributors to this monograph. ZL, PA, and JHA declare that they have no competing interests.

Associate Professor of Medicine

Innsbruck Medical University

Innsbruck

Austria

利益冲突披露
CP declares that he has no competing interests.

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