BMJ Best Practice
最后审核时间： 十月 2018
最近更新时间： 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 精神状态改变
  • 肌强直
  • 自主神经功能障碍
全部具体信息

其他诊断因素

  • 铁缺乏病史
  • Wilson 病病史
全部具体信息

危险因素

  • 暴露于抗精神病药物
  • 突然停用多巴胺能药物
  • 结构性脑部异常
  • 高龄
全部具体信息

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 血清肌酸激酶 (CK)
  • 基本代谢指标
  • 脑部 CT 扫描
全部具体信息

需要考虑的检查

  • 血清铁
全部具体信息

治疗流程

急性

首次发作

疾病持续状态

复发

贡献者

作者 查看所有

Associate Professor

Harvard Medical School

Boston

MA

利益冲突披露
RJG is occasionally retained as an expert witness in tort claims where NMS is alleged to have occurred. He is an author of several references cited in this monograph.

Dr Ronald J. Gurrera would like to gratefully acknowledge Dr Peter F. Buckley, a previous contributor to this monograph. PFB is on the advisory board (a voluntary, uncompensated role) of the Neuroleptic Malignant Syndrome Information Service. He is also a consultant to Janssen Pharmaceutica and the National Institute of Mental Health (NIMH). He is conducting or has recently conducted research with funding support from AstraZeneca, NIMH, Janssen Pharmaceutica, Pfizer, Solvay, and Wyeth. Previous consultancy and research support has been from Abbott, Alamo Pharmaceuticals, AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Lundbeck, Janssen Pharmaceutica, Merck, NIMH, Roche Diagnostics, Pfizer, Solvay, and Wyeth. PFB has no patents or stock in any company. He is an author of several references cited in this monograph. PFB is a co-investigator on a study also involving Dr John Lauriello and Dr Daniel R. Wilson, who were reviewers for this monograph.

同行评议专家 查看所有

Consultant Psychiatrist

Honorary Senior Clinical Lecturer

Royal Cornhill Hospital

Aberdeen

UK

利益冲突披露
AH declares that she has no competing interests.

Professor and Chair

Department of Psychiatry

University of Missouri-Columbia

Columbia

MO

利益冲突披露
JL declares that he has no competing interests.

Assistant Professor

Department of Psychiatry

University of Missouri-Columbia

Columbia

MO

利益冲突披露
GG declares that he has no competing interests.

使用此内容应接受我们的免责声明。