BMJ Best Practice
最后审核时间: 一月 2019
最近更新时间: 十月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 咳嗽
  • 咳痰
  • 湿啰音、高音调吸气性喘鸣和干啰音

其他诊断因素

  • 疲劳
  • 咯血
  • 鼻窦炎
  • 体重减轻

危险因素

  • 囊性纤维化
  • 宿主免疫缺陷
  • 既往感染
  • 支气管气道的先天性疾病

诊断性检查

首要检查

  • 胸部 X 线检查(CXR)
  • 高分辨率胸部 CT 扫描
  • 全血细胞计数(FBC)
  • 痰培养和药敏
全部具体信息

需要考虑的检查

  • 支气管活检和纤毛电子显微镜镜检
  • 囊性纤维化跨膜调节 (CFTR) 蛋白基因突变检测
  • 吞咽功能检查
  • 痰液 pH 值监测
全部具体信息

治疗流程

疾病持续状态

贡献者

Professor of Medicine

Chief, Division of Pulmonary, Critical Care and Sleep Medicine

Georgetown University Hospital

Washington

DC

利益冲突披露
AEOD has been compensated by the following companies for consultation regarding new drug development and clinical trials: Bayer, Xellia, Novartis, Insmed. AEOD has been or is the Principal Investigator for trials sponsored by the following companies (research funding provided directly to Georgetown University): Bayer, Insmed, Aradigm, Gilead. AEOD is the Principal Investigator for the Bronchiectasis Research Registry, sponsored by the COPD Foundation (research funding provided directly to Georgetown University). AEOD is the author of a reference cited in this monograph.

Dr Anne E. O'Donnell would like to gratefully acknowledge Dr Pamela J. McShane and Dr Sangeeta M. Bhorade, previous contributors to this monograph. PJM and SMB declare that they have no competing interests.

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Consultant Physician

Honorary Senior Lecturer

Imperial College Healthcare Trust

Hammersmith Hospital

London

UK

利益冲突披露
PWI declares that he has no competing interests.

Associate Professor of Medicine

Stanford University

Stanford

Staff Physician

US Department of Veterans Affairs

Palo Alto Health Care System

Palo Alto

CA

利益冲突披露
WK declares that he has no competing interests.

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