在未来妊娠中,妊娠滋养细胞疾病 (GTD) 复发的风险为 1%(或大约是基线风险的 10 倍)。[14]Berkowitz RS, Tuncer ZS, Bernstein MR, et al. Management of gestational trophoblastic diseases: subsequent pregnancy experience. Semin Oncol. 2000;27:678-685.http://www.ncbi.nlm.nih.gov/pubmed/11130475?tool=bestpractice.com[16]Sand PK, Lurain JR, Brewer JI. Repeat gestational trophoblastic disease. Obstet Gynecol. 1984;63:140-144.http://www.ncbi.nlm.nih.gov/pubmed/6320076?tool=bestpractice.com在后续妊娠时应对患者密切随访。在完全性葡萄胎妊娠患者中,约 20% 发生恶性妊娠滋养细胞肿瘤 (GTN)。[19]Soper JT, Mutch DG, Schink JC. Diagnosis and treatment of gestational trophoblastic disease: ACOG Practice Bulletin No. 53. Gynecol Oncol. 2004;93:575-585.http://www.ncbi.nlm.nih.gov/pubmed/15196847?tool=bestpractice.com约 5% 的部分性葡萄胎妊娠患者会发生恶性 GTN。[19]Soper JT, Mutch DG, Schink JC. Diagnosis and treatment of gestational trophoblastic disease: ACOG Practice Bulletin No. 53. Gynecol Oncol. 2004;93:575-585.http://www.ncbi.nlm.nih.gov/pubmed/15196847?tool=bestpractice.com这些疾病的治愈率超过 95%。[19]Soper JT, Mutch DG, Schink JC. Diagnosis and treatment of gestational trophoblastic disease: ACOG Practice Bulletin No. 53. Gynecol Oncol. 2004;93:575-585.http://www.ncbi.nlm.nih.gov/pubmed/15196847?tool=bestpractice.com