对治疗的依从性至关重要,应对患者予以鼓励。 钙应与食物一起分次服用。 严格依从高钙低磷的饮食指南非常重要。 饮食处方需根据患者的年龄、血清钙和血磷水平、对口服钙剂的耐受程度来制定[53]Kovacs CS, Fuleihan GE. Calcium and bone disorders during pregnancy and lactation. Endocrinol Metab Clin N Am. 2006 Mar;35(1):21-51, v.http://www.ncbi.nlm.nih.gov/pubmed/16310641?tool=bestpractice.com[54]Greer FR, Krebs NF; American Academy of Pediatrics Committee on Nutrition. Optimizing bone health and calcium intakes of infants, children, and adolescents. Pediatrics. 2006 Feb;117(2):578-85.http://pediatrics.aappublications.org/content/117/2/578.fullhttp://www.ncbi.nlm.nih.gov/pubmed/16452385?tool=bestpractice.com 。应鼓励患者戒烟。
如果假性甲状旁腺功能减退症患者想要受孕,应考虑进行胚胎植入前遗传学诊断 (preimplantation genetic diagnosis, PGD),以减少和尽可能避免把 GNAS 突变传递给胎儿。通过胚胎植入前遗传学诊断,可以选择植入没有 GNAS 突变的胚胎。[55]Lietman SA. Preimplantation genetic diagnosis for hereditary endocrine disease. Endocr Pract. 2011 Jul-Aug;17 Suppl 3:28-32.http://www.ncbi.nlm.nih.gov/pubmed/21550946?tool=bestpractice.com