女性性功能障碍与心理健康状况差和对伴侣有消极情绪的相关性最强，而不是与血清激素（或激素代谢产物）水平相关。
阅读更多在欲望/兴趣障碍中，一定不能误解随着年龄和关系持续时间发生的正常变化。当缺乏预期的性欲并且在性活动期间不能激发欲望（以及快感、唤起和兴奋）并导致苦恼时，诊断为性欲障碍。
最常见的综合征是缺乏初始欲望、主动唤起（心理上的性兴奋）程度低，以至于任何性接触都不能激发欲望、很少或没有性高潮。
考虑到采集信息较为敏感以及在初次就诊时不愿意透露或羞于启齿，临床医生在与患者接触过程中应当持续评估相关信息，并整合到治疗中。
治疗包括心理教育、认知行为疗法 (CBT)、性治疗、正念与心理治疗，偶尔使用药物治疗。
女性性功能障碍包括典型的、涉及多病因的系列障碍和包括性兴趣/唤起障碍 (SIAD)、女性性高潮障碍 (FOD)、生殖器-盆腔疼痛/侵入障碍 (GPPPD)，这些障碍经常组合成互相重叠的阴道痉挛和性交困难诊断。American Psychiatric Association: DSM-5 development
阅读更多只有当症状持续存在，且与苦恼相关时，才诊断功能障碍或障碍，应当记录苦恼的程度。[1]Basson R, Leiblum S, Brotto L, et al. Definitions of women's sexual dysfunctions reconsidered: advocating expansion and revision. J Psychosom Obstet Gynaecol. 2003;24:221-229.http://www.ncbi.nlm.nih.gov/pubmed/14702882?tool=bestpractice.com心理健康状况差、窘迫、[2]Maserejian NN, Shifren JL, Parish J, et al. The presentation of hypoactive sexual desire disorder in premenopausal women. J Sex Med. 2010;7:3439-3448.http://www.ncbi.nlm.nih.gov/pubmed/20646184?tool=bestpractice.com和伴侣间情感亲密水平低与功能障碍密切相关，[3]Bancroft J, Loftus J, Long JS. Distress about sex: a national survey of women in heterosexual relationships. Arch Sex Behav. 2003;32:193-208.http://www.ncbi.nlm.nih.gov/pubmed/12807292?tool=bestpractice.com[4]Hartmann U, Philippsohn S, Heiser K, et al. Low desire in midlife and older women: personality factors, psychosocial development, present sexuality. Menopause. 2004;11:726-740.http://www.ncbi.nlm.nih.gov/pubmed/15543025?tool=bestpractice.com[5]Avis NE, Stellato R, Crawford S, et al. Is there an association between menopause status and sexual functioning? Menopause. 2000;7:297-309.http://www.ncbi.nlm.nih.gov/pubmed/10993029?tool=bestpractice.com但与血清性激素水平不相关。[6]Dennerstein L, Dudley E, Burger H. Are changes in sexual functioning during mid-life due to aging or menopause? Fertil Steril. 2001;76:456-460.http://www.ncbi.nlm.nih.gov/pubmed/11532464?tool=bestpractice.com[7]Santoro N, Torrens J, Crawford S, et al. Correlates of circulating androgens in midlife women: the study of women's health across the nation. J Clin Endocrinol Metab. 2005;90:4836-4845.http://jcem.endojournals.org/cgi/content/full/90/8/4836http://www.ncbi.nlm.nih.gov/pubmed/15840738?tool=bestpractice.com[8]Davis SR, Davison SL, Donath S, et al. Circulating androgen levels and self-reported sexual function in women. JAMA. 2005;294:91-96.http://jama.ama-assn.org/cgi/content/full/294/1/91http://www.ncbi.nlm.nih.gov/pubmed/15998895?tool=bestpractice.com[9]Basson R, Brotto LA, Petkau AJ, et al. Role of androgens in women’s sexual dysfunction. Menopause. 2010;17:962-971.http://www.ncbi.nlm.nih.gov/pubmed/20539247?tool=bestpractice.com[10]Erekson EA, Martin DK, Zhu K, et al. Sexual function in older women after oophorectomy. Obstet Gynecol. 2012;120:833-842.http://www.ncbi.nlm.nih.gov/pubmed/22996101?tool=bestpractice.com[11]van Anders SM. Testosterone and sexual desire in healthy women and men. Arch Sex Behav. 2012;41:1471-1484.http://www.ncbi.nlm.nih.gov/pubmed/22552705?tool=bestpractice.com
阴道痉挛和性交困难现在统称为 GPPPD，是一组特殊的疾病，本专题中不予讨论；然而在性交困难专题中可获得更多信息。
考虑到在持续性生殖器唤起障碍方面仅有有限的研究，[12]Facelle TM, Sadeghi-Nejad H, Goldmeier D. Persistent genital arousal disorder: characterization, etiology, and management. J Sex Med. 2013;10:439-450.http://www.ncbi.nlm.nih.gov/pubmed/23157369?tool=bestpractice.com本专题不予讨论其病理生理学机制和治疗。
