证据评分
性满意度：有高质量证据表明，使用外用雌激素治疗可改善雌激素缺乏的外阴阴道萎缩妇女的性满意度。[102]Johnston JJ, Farrell S, Bouchard C, et al. The detection and management of vaginal atrophy. J Obstet Gynaecol Can. 2004;26:503-508.http://www.ncbi.nlm.nih.gov/pubmed/15151738?tool=bestpractice.com[103]Mainini G, Scaffa C, Rotondi M, et al. Local estrogen replacement therapy in postmenopausal atrophic vaginitis: efficacy and safety of low dose 17 beta-estradiol vaginal tablets. Clin Exp Obstet Gynecol. 2005;32:111-113.http://www.ncbi.nlm.nih.gov/pubmed/16108394?tool=bestpractice.com[104]Long CY, Liu CM, Hsu SC, et al. A randomized comparative study of the effects of oral and topical estrogen therapy on the vaginal vascularization and sexual function in hysterectomized post menopausal women. Menopause. 2006;13:737-743.http://www.ncbi.nlm.nih.gov/pubmed/16946685?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
性满意度：有高质量证据表明，使用外用雌激素治疗可改善雌激素缺乏的外阴阴道萎缩妇女的性满意度。[102]Johnston JJ, Farrell S, Bouchard C, et al. The detection and management of vaginal atrophy. J Obstet Gynaecol Can. 2004;26:503-508.http://www.ncbi.nlm.nih.gov/pubmed/15151738?tool=bestpractice.com[103]Mainini G, Scaffa C, Rotondi M, et al. Local estrogen replacement therapy in postmenopausal atrophic vaginitis: efficacy and safety of low dose 17 beta-estradiol vaginal tablets. Clin Exp Obstet Gynecol. 2005;32:111-113.http://www.ncbi.nlm.nih.gov/pubmed/16108394?tool=bestpractice.com[104]Long CY, Liu CM, Hsu SC, et al. A randomized comparative study of the effects of oral and topical estrogen therapy on the vaginal vascularization and sexual function in hysterectomized post menopausal women. Menopause. 2006;13:737-743.http://www.ncbi.nlm.nih.gov/pubmed/16946685?tool=bestpractice.com
