证据评分
减少夜间进食：少量证据显示，睡眠相关进食障碍患者，少部分患者用托吡酯可能会帮助减少夜间进食，尽管也会存在耐受性问题。[56]Winkelman JW. Treatment of nocturnal eating syndrome and sleep-related eating disorder with topiramate. Sleep Med. 2003;4:243-246.http://www.ncbi.nlm.nih.gov/pubmed/14592329?tool=bestpractice.com[57]Winkelman JW. Efficacy and tolerability of open-label topiramate in the treatment of sleep-related eating disorder: a retrospective case series. J Clin Psychiatry. 2006;67:1729-1734.http://www.ncbi.nlm.nih.gov/pubmed/17196052?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
减少夜间进食：少量证据显示，睡眠相关进食障碍患者，少部分患者用托吡酯可能会帮助减少夜间进食，尽管也会存在耐受性问题。[56]Winkelman JW. Treatment of nocturnal eating syndrome and sleep-related eating disorder with topiramate. Sleep Med. 2003;4:243-246.http://www.ncbi.nlm.nih.gov/pubmed/14592329?tool=bestpractice.com[57]Winkelman JW. Efficacy and tolerability of open-label topiramate in the treatment of sleep-related eating disorder: a retrospective case series. J Clin Psychiatry. 2006;67:1729-1734.http://www.ncbi.nlm.nih.gov/pubmed/17196052?tool=bestpractice.com
氯硝西泮对快速动眼行为障碍的效果：缺乏有效证据支持氯硝西泮对快速动眼行为障碍的有效性。[60]Schenck CH, Mahowald MW. Polysomnographic, neurologic, psychiatric, and clinical outcome report on 70 consecutive cases with REM sleep behavior disorder (RBD): Sustained clonazepam efficacy in 89.5% of 57 treated patients. Cleve Clin J Med. 1990;57(Suppl):S9-S23.
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
氯硝西泮对快速动眼行为障碍的效果：缺乏有效证据支持氯硝西泮对快速动眼行为障碍的有效性。[60]Schenck CH, Mahowald MW. Polysomnographic, neurologic, psychiatric, and clinical outcome report on 70 consecutive cases with REM sleep behavior disorder (RBD): Sustained clonazepam efficacy in 89.5% of 57 treated patients. Cleve Clin J Med. 1990;57(Suppl):S9-S23.
