口腔白斑病

需要进行定期随访。每 4~6 个月都要进行仔细检查。若临床病损发生变化，则需要进行进一步活检，以确定上皮异常增生程度是否增加，或有没有出现明显的恶性转化。尽管相关研究仍在进行，在特定随访中也可以使用毛刷活检和/或常规活检以筛查恶性转变的分子标志物。[15]Zhang L, Rosin MP. Loss of heterozygosity: a potential tool in management of oral premalignant lesions? J Oral Pathol Med. 2001;30:513-520.http://www.ncbi.nlm.nih.gov/pubmed/11555152?tool=bestpractice.com[96]Patel V, Leethanakul C, Gutkind JS. New approaches to the understanding of the molecular basis of oral cancer. Crit Rev Oral Biol Med. 2001;12:55-63.http://www.ncbi.nlm.nih.gov/pubmed/11349962?tool=bestpractice.com[94]Zhang L, Cheung KJ Jr, Lam WL, et al. Increased genetic damage in oral leukoplakia from high risk sites: potential impact on staging and clinical management. Cancer. 2001;91:2148-2155.http://www3.interscience.wiley.com/cgi-bin/fulltext/82003264/HTMLSTARThttp://www.ncbi.nlm.nih.gov/pubmed/11391596?tool=bestpractice.com