产前超声波扫描
在妊娠18周时可通过常规产前胎儿超声识别有无唇裂的存在。如产前超声检查有阳性结果,建议母体-胎儿专家介入和进行遗传学咨询。[40]Gagnon A, Wilson RD, Allen VM, et al; Society of Obstetricians and Gynaecologists of Canada. Evaluation of prenatally diagnosed structural congenital anomalies. J Obstet Gynaecol Can. 2009;31:875-881.http://www.ncbi.nlm.nih.gov/pubmed/19941713?tool=bestpractice.com在系统的文献综述中发现口腔颌面裂通过常规二维超声检出率较低。但是,三维超声检查唇裂伴或不伴腭裂的诊断准确率较高。三维超声不能提高单纯腭裂的检测准确性。[39]Maarse W, Bergé SJ, Pistorius L, et al. Diagnostic accuracy of transabdominal ultrasound in detecting prenatal cleft lip and palate: a systematic review. Ultrasound Obstet Gynecol. 2010;35:495-502.http://onlinelibrary.wiley.com/doi/10.1002/uog.7472/fullhttp://www.ncbi.nlm.nih.gov/pubmed/20235140?tool=bestpractice.com这些知识为父母提供了收集信息和获取可用支持系统的机会。向裂和颅面团队外科医生进行产前咨询,以解释和制订产后初始治疗计划,有助于父母理解和参与到这一疾病的复杂、多学科管理中。