成人患病无种族和性别差异。不过,儿童得这种病的几率是成人的两倍。男童得这种病的几率是女童的两倍。[1]Robinson A, Beech T, McDermott AL, et al. Investigation and management of adult periorbital or orbital cellulitis. J Laryngol Otol. 2007;121:545-547.http://www.ncbi.nlm.nih.gov/pubmed/17164026?tool=bestpractice.com在全球范围内本病多发生于冬季,是因为在冬季患鼻窦炎的风险增加。依据既往报道,在乙型流感嗜血杆菌疫苗常规应用之前,由乙型流感嗜血杆菌血行播散引起的眶周蜂窝织炎发病率高达80%。[2]Ambati B, Ambati J, Azar N, et al. Periorbital and orbital cellulitis before and after the advent of Haemophilus influenzae type b vaccination. Ophthalmology. 2000;107:1450-1453.http://www.ncbi.nlm.nih.gov/pubmed/10919886?tool=bestpractice.com应用乙型流感嗜血杆菌疫苗后,由乙型留学嗜血杆菌导致的眶周蜂窝织炎很少见。[2]Ambati B, Ambati J, Azar N, et al. Periorbital and orbital cellulitis before and after the advent of Haemophilus influenzae type b vaccination. Ophthalmology. 2000;107:1450-1453.http://www.ncbi.nlm.nih.gov/pubmed/10919886?tool=bestpractice.com