丹曲林
丹曲林是一种骨骼肌松弛药,可抑制肌质网中钙释放。由于这种药物可以在骨骼肌异常持续收缩期间减少骨骼肌产生的热量,因此先前已用于恶性高热和神经阻滞剂恶性综合征患者。[32]Bouchama A, Cafege A, Devol EB, et al. Ineffectiveness of dantrolene sodium in the treatment of heatstroke. Crit Care Med. 1991;19:176-180.http://www.ncbi.nlm.nih.gov/pubmed/1989755?tool=bestpractice.com丹曲林之前已在小型试验中进行过研究,此药作为当前治疗方法的辅助治疗获得了全新关注。[32]Bouchama A, Cafege A, Devol EB, et al. Ineffectiveness of dantrolene sodium in the treatment of heatstroke. Crit Care Med. 1991;19:176-180.http://www.ncbi.nlm.nih.gov/pubmed/1989755?tool=bestpractice.com[29]Bouchama A, Dehbi M, Chaves-Carballo E. Cooling and hemodynamic management in
heatstroke: practical recommendations. Crit Care. 2007;11:R54.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206402/http://www.ncbi.nlm.nih.gov/pubmed/17498312?tool=bestpractice.com