Ausch C, Madoff RD, Gnant M, et al. Aetiology and surgical management of toxic megacolon. Colorectal Dis. 2006 Mar;8(3):195-201.
Sheth SG, LaMont JT. Toxic megacolon. Lancet. 1998 Feb 14;351(9101):509-13.
Klobuka AJ, Markelov A. Current status of surgical treatment for fulminant clostridium difficile colitis. World J Gastrointest Surg. 2013 Jun 27;5(6):167-72.
Teeuwen PH, Stommel MW, Bremers AJ, et al. Colectomy in patients with acute colitis: a systematic review. J Gastrointest Surg. 2009 Apr;13(4):676-86.
Berman L, Carling T, Fitzgerald TN, et al. Defining surgical therapy for pseudomembranous colitis with toxic megacolon. J Clin Gastroenterol. 2008 May-Jun;42(5):476-80.
1. Marshak RH, Lester LJ. Megacolon a complication of ulcerative colitis. Gastroenterology. 1950 Dec;16(4):768-72.
2. Grieco MB, Bordan DL, Geiss AC, et al. Toxic megacolon complicating Crohn's colitis. Ann Surg. 1980 Jan;191(1):75-80.
3. Greenstein AJ, Sachar DB, Gibas A, et al. Outcome of toxic dilatation in ulcerative and Crohn's colitis. J Clin Gastroenterol. 1985 Apr;7(2):137-43.
4. Ausch C, Madoff RD, Gnant M, et al. Aetiology and surgical management of toxic megacolon. Colorectal Dis. 2006 Mar;8(3):195-201.
5. Dallal RM, Harbrecht BG, Boujoukas AJ, et al. Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications. Ann Surg. 2002 Mar;235(3):363-72.
6. Doshi R, Desai J, Shah Y, et al. Incidence, features, in-hospital outcomes and predictors of in-hospital mortality associated with toxic megacolon hospitalizations in the United States. Intern Emerg Med. 2018 Sep;13(6):881-7.
7. Bellary SV, Isaacs P. Toxic megacolon (TM) due to Salmonella. J Clin Gastroenterol. 1990 Oct;12(5):605-7.
8. Tiao MM, Huang HC, Huang CB, et al. Toxic megacolon in Salmonella colitis: report of two cases. Acta Paediatr Taiwan. 2000 Jan-Feb;41(1):43-6.
9. Upadhyay AK, Neely JA. Toxic megacolon and perforation caused by Shigella. Br J Surg. 1989 Nov;76(11):1217.
10. Anderson JB, Tanner AH, Brodribb AJ. Toxic megacolon due to Campylobacter colitis. Int J Colorectal Dis. 1986 Jan;1(1):58-9.
11. McGregor A, Brown M, Thway K, et al. Fulminant amoebic colitis following loperamide use. J Travel Med. 2007 Jan-Feb;14(1):61-2.
12. Beaugerie L, Ngo Y, Goujard F, et al. Etiology and management of toxic megacolon in patients with human immunodeficiency virus infection. Gastroenterology. 1994 Sep;107(3):858-63.
13. Cooper HS, Raffensperger EC, Jonas L, et al. Cytomegalovirus inclusions in patients with ulcerative colitis and toxic dilation requiring colonic resection. Gastroenterology. 1977 Jun;72(6):1253-6.
14. Criscuoli V, Rizzuto MR, Gallo E, et al. Toxic megacolon and human Cytomegalovirus in a series of severe ulcerative colitis patients. J Clin Virol. 2015 May;66:103-6.
15. Present DH. Toxic megacolon. Med Clin North Am. 1993 Sep;77(5):1129-48.
16. Atherton LD, Leib ES, Kaye MD. Toxic megacolon associated with methotrexate therapy. Gastroenterology. 1984 Jun;86(6):1583-8.
17. Lee FY, Lin HY, Pan S, et al. Gold-induced fulminant colitis in a patient with psoriatic arthritis. J Clin Gastroenterol. 1988 Feb;10(1):116-7.
18. de Gara CJ, Gagic N, Arnold A, et al. Toxic megacolon associated with anticancer chemotherapy. Can J Surg. 1991 Aug;34(4):339-41.
19. Gan SI, Beck PL. A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management. Am J Gastroenterol. 2003 Nov;98(11):2363-71.
20. Sheth SG, LaMont JT. Toxic megacolon. Lancet. 1998 Feb 14;351(9101):509-13.
21. Solomon K. The host immune response to Clostridium difficile infection. Ther Adv Infect Dis. 2013 Feb;1(1):19-35.
22. McDonald LC, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018 Mar 19;66(7):987-94.
23. Imbriaco M, Balthazar EJ. Toxic megacolon: role of CT in evaluation and detection of complications. Clin Imaging. 2001 Sep-Oct;25(5):349-54.
24. Jalan KN, Sircus W, Card WI, et al. An experience of ulcerative colitis. I. Toxic dilation in 55 cases. Gastroenterology. 1969 Jul;57(1):68-82.
25. Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017 Mar;43(3):304-77.
26. Rhodes A, Phillips G, Beale R, et al. The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study). Intensive Care Med. 2015 Sep;41(9):1620-8.
27. Levy MM, Rhodes A, Phillips GS, et al. Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study. Intensive Care Med. 2014 Nov;40(11):1623-33.
28. Seymour CW, Gesten F, Prescott HC, et al. Time to treatment and mortality during mandated emergency care for sepsis. N Engl J Med. 2017 Jun 8;376(23):2235-44.
29. Zar FA, Bakkanagari SR, Moorthi KM, et al. A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity. Clin Infect Dis. 2007 Aug 1;45(3):302-7.
30. Cocanour CS. Best strategies in recurrent or persistent Clostridium difficile infection. Surg Infect (Larchmt). 2011 Jun;12(3):235-9.
31. Kim PK, Huh HC, Cohen HW, et al. Intracolonic vancomycin for severe Clostridium difficile colitis. Surg Infect (Larchmt). 2013 Dec;14(6):532-9.
32. Klobuka AJ, Markelov A. Current status of surgical treatment for fulminant clostridium difficile colitis. World J Gastrointest Surg. 2013 Jun 27;5(6):167-72.
33. Teeuwen PH, Stommel MW, Bremers AJ, et al. Colectomy in patients with acute colitis: a systematic review. J Gastrointest Surg. 2009 Apr;13(4):676-86.
34. National Patient Safety Agency. Reducing the harm caused by misplaced nasogastric feeding tubes in adults, children and infants (Patient Safety Alert NPSA/2011/PSA002). Mar 2011 [internet publication].
35. Neal MD, Alverdy JC, Hall DE, et al. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease. Ann Surg. 2011 Sep;254(3):423-7.
36. Pola S, Patel D, Ramamoorthy S, et al. Strategies for the care of adults hospitalized for active ulcerative colitis. Clin Gastroenterol Hepatol. 2012 Dec;10(12):1315-25.
37. Actis GC, Ottobrelli A, Pera A, et al. Continuously infused cyclosporine at low dose is sufficient to avoid emergency colectomy in acute attacks of ulcerative colitis without the need for high-dose steroids. J Clin Gastroenterol. 1993 Jul;17(1):10-3.
38. van Geenen EJ, Sachar DB. Infliximab in Crohn's disease-associated toxic megacolon. J Clin Gastroenterol. 2012 Apr;46(4):321-3.
39. Sinagra E, Orlando A, Renna S, et al. Is really megacolon a contraindication to infliximab in Crohn's disease? Acta Gastroenterol Belg. 2013 Dec;76(4):442-4.
40. Narabayashi K, Inoue T, Sakanaka T, et al. Oral tacrolimus for megacolon in patients with severe ulcerative colitis. Intern Med. 2014;53(16):1755-8.
41. Hayashi R, Ueno Y, Tanaka S, et al. Two cases of severe ulcerative colitis with colonic dilatation resolved with tacrolimus therapy. Case Rep Gastroenterol. 2015 Jul 31;9(2):272-7.
42. Mitsuyama K, Sata M. Therapeutic leukocytapheresis in inflammatory bowel disease: clinical efficacy and mechanisms of action. Cytotherapy. 2009;11(2):229-37.
43. Kanai T, Hibi T, Watanabe M. The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease. Expert Opin Biol Ther. 2006 May;6(5):453-66.
44. Yokoyama Y, Matsuoka K, Kobayashi T, et al. A large-scale, prospective, observational study of leukocytapheresis for ulcerative colitis: treatment outcomes of 847 patients in clinical practice. J Crohns Colitis. 2014 Sep;8(9):981-91.
45. Cammarota G, Ianiro G, Gasbarrini A. Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review. J Clin Gastroenterol. 2014 Sep;48(8):693-702.
46. Gweon TG, Lee KJ, Kang DH, et al. A case of toxic megacolon caused by Clostridium difficile infection and treated with fecal microbiota transplantation. Gut Liver. 2015 Mar;9(2):247-50.
47. Yu S, Abdelkarim A, Nawras A, et al. Fecal transplant for treatment of toxic megacolon associated with Clostridium difficile colitis in a patient with Duchenne muscular dystrophy. Am J Ther. 2016 Mar-Apr;23(2):e609-13.
48. Trudel JL, Deschenes M, Mayrand S, et el. Toxic megacolon complicating pseudomembranous enterocolitis. Dis Colon Rectum. 1995 Oct;38(10):1033-8.
49. Grant CS, Dozois RR. Toxic megacolon: ultimate fate of patients after successful medical management. Am J Surg. 1984 Jan;147(1):106-10.
50. Berman L, Carling T, Fitzgerald TN, et al. Defining surgical therapy for pseudomembranous colitis with toxic megacolon. J Clin Gastroenterol. 2008 May-Jun;42(5):476-80.
51. Perera AD, Akbari RP, Cowher MS, et al. Colectomy for fulminant Clostridium difficile colitis: predictors of mortality. Am Surg. 2010 Apr;76(4):418-21.
52. Osman KA, Ahmed MH, Hamad MA, et al. Emergency colectomy for fulminant Clostridium difficile colitis: striking the right balance. Scand J Gastroenterol. 2011 Oct;46(10):1222-7.
53. Borgia G, Maraolo AE, Foggia M, et al. Fecal microbiota transplantation for Clostridium difficile infection: back to the future. Expert Opin Biol Ther. 2015 Jul;15(7):1001-14.
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