应向患者提示可能导致高凝状态的因素。鼓励调整生活方式如戒烟，肥胖的话建议减肥。高风险状态下的患者如术后、急症入院、活动障碍、打石膏以及长途航班（超过 4 小时），应该考虑血栓预防。建议有静脉血栓栓塞个人史或家族史的患者避免应用复方口服避孕药、口服激素替代疗法和选择性雌二醇受体调节剂。[3]Baglin T, Gray E, Greaves M, et al; British Committee for Standards in Haematology. Clinical guidelines for testing for heritable thrombophilia. Br J Haematol. 2010;149:209-220.http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2009.08022.x/fullhttp://www.ncbi.nlm.nih.gov/pubmed/20128794?tool=bestpractice.com [ 
]How do different combined oral contraceptives compare in terms of the risk of venous thrombosis?http://cochraneclinicalanswers.com/doi/10.1002/cca.933/full显示答案
