临床治疗:伊维菌素顿服治疗 CLM 的治愈率是77% 至 100%,阿苯达唑顿服治疗 CLM 的治愈率是46%,P = 0.017。差异具有统计学意义。[28]Bouchaud O, Houzé S, Schiemann R, et al. Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis. 2000;31:493-498. [Erratum in: Clin Infect Dis. 2001;32:523.]http://cid.oxfordjournals.org/content/31/2/493.fullhttp://www.ncbi.nlm.nih.gov/pubmed/10987711?tool=bestpractice.com[44]Caumes E, Carriere J, Guermonprez G, et al. Dermatoses associated with travel to tropical countries: a prospective study of the diagnosis and management of 269 patients presenting to a tropical disease unit. Clin Infect Dis. 1995;20:542-548.http://www.ncbi.nlm.nih.gov/pubmed/7756473?tool=bestpractice.com[45]Van den Enden E, Stevens A, Van Gompel A. Treatment of cutaneous larva migrans. N Engl J Med. 1998;339:1246-1247.http://www.ncbi.nlm.nih.gov/pubmed/9786758?tool=bestpractice.com[46]Caumes E, Carriere J, Datry A, et al. A randomized trial of ivermectin versus albendazole for the treatment of cutaneous larva migrans. Am J Trop Med Hyg. 1993;49:641-644.http://www.ncbi.nlm.nih.gov/pubmed/8250105?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
临床治疗:伊维菌素顿服治疗 CLM 的治愈率是77% 至 100%,阿苯达唑顿服治疗 CLM 的治愈率是46%,P = 0.017。差异具有统计学意义。[28]Bouchaud O, Houzé S, Schiemann R, et al. Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis. 2000;31:493-498. [Erratum in: Clin Infect Dis. 2001;32:523.]http://cid.oxfordjournals.org/content/31/2/493.fullhttp://www.ncbi.nlm.nih.gov/pubmed/10987711?tool=bestpractice.com[44]Caumes E, Carriere J, Guermonprez G, et al. Dermatoses associated with travel to tropical countries: a prospective study of the diagnosis and management of 269 patients presenting to a tropical disease unit. Clin Infect Dis. 1995;20:542-548.http://www.ncbi.nlm.nih.gov/pubmed/7756473?tool=bestpractice.com[45]Van den Enden E, Stevens A, Van Gompel A. Treatment of cutaneous larva migrans. N Engl J Med. 1998;339:1246-1247.http://www.ncbi.nlm.nih.gov/pubmed/9786758?tool=bestpractice.com[46]Caumes E, Carriere J, Datry A, et al. A randomized trial of ivermectin versus albendazole for the treatment of cutaneous larva migrans. Am J Trop Med Hyg. 1993;49:641-644.http://www.ncbi.nlm.nih.gov/pubmed/8250105?tool=bestpractice.com