尽管移行的幼虫给患者造成相当大的压力和不适。几乎所有的 CLM患者 预后良好。对于生活在疫区经常被感染的个体，其生活质量受到相当大的影响。[8]Schuster A, Lesshafft H, Talhari S, et al. Life quality impairment caused by hookworm-related cutaneous larva migrans in resource-poor communities in Manaus, Brazil. PLoS Negl Trop Dis. 2011;5:e1355.http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001355http://www.ncbi.nlm.nih.gov/pubmed/22087341?tool=bestpractice.com尽管据报道，一些患者的临床症状存在达数月之久。但通常在不治疗的情况下，大约 2 至 8 周后，移行的幼虫在皮肤内死亡。 [20]Blackwell V, Vega-Lopez F. Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveller. Br J Dermatol. 2001;145:434-437.http://www.ncbi.nlm.nih.gov/pubmed/11531833?tool=bestpractice.com一旦治疗，通常在 1 周内，症状和皮肤病变迅速消失。[28]Bouchaud O, Houzé S, Schiemann R, et al. Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis. 2000;31:493-498. [Erratum in: Clin Infect Dis. 2001;32:523.]http://cid.oxfordjournals.org/content/31/2/493.fullhttp://www.ncbi.nlm.nih.gov/pubmed/10987711?tool=bestpractice.com
复发
治疗后好转的患者可能会再次出现症状和皮肤病变，这可能是因为药物只是破坏了钩虫幼虫，但并未完全杀死这些幼虫。复发通常发生在初期表现后的几周内，绝大多数病例重复治疗有效。[2]Tremblay A, MacLean JD, Gyorkos T, et al. Outbreak of cutaneous larva migrans in a group of travellers. Trop Med Int Health. 2000;5:330-334.http://onlinelibrary.wiley.com/doi/10.1046/j.1365-3156.2000.00557.x/fullhttp://www.ncbi.nlm.nih.gov/pubmed/10886795?tool=bestpractice.com[20]Blackwell V, Vega-Lopez F. Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveller. Br J Dermatol. 2001;145:434-437.http://www.ncbi.nlm.nih.gov/pubmed/11531833?tool=bestpractice.com[28]Bouchaud O, Houzé S, Schiemann R, et al. Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis. 2000;31:493-498. [Erratum in: Clin Infect Dis. 2001;32:523.]http://cid.oxfordjournals.org/content/31/2/493.fullhttp://www.ncbi.nlm.nih.gov/pubmed/10987711?tool=bestpractice.com
与 CLM 有关的毛囊炎
由动物钩虫幼虫引起的毛囊炎可能需要多轮抗蠕虫药物治疗。[4]Caumes E, Ly F, Bricaire F. Cutaneous larva migrans with folliculitis: report of seven cases and review of the literature. Br J Dermatol. 2002;146:314-316.http://www.ncbi.nlm.nih.gov/pubmed/11903247?tool=bestpractice.com
