非典型肺炎

索利霉素

在一项随机对照试验中，在治疗社区获得性细菌性肺炎时，口服索利霉素（一种大环内酯类药物）不劣于口服莫西沙星。[65]Barrera CM, Mykietiuk A, Metev H, et al; SOLITAIRE-ORAL Pneumonia Team. Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL). Lancet Infect Dis. 2016;16:421-430.http://www.ncbi.nlm.nih.gov/pubmed/26852726?tool=bestpractice.com研究证明，有效性、耐受性和安全性特征使其成为一种有前景的治疗。[66]Zhanel GG, Hartel E, Adam H, et al. Solithromycin: a novel fluoroketolide for the treatment of community-acquired bacterial pneumonia. Drugs. 2016;76:1737-1757.http://www.ncbi.nlm.nih.gov/pubmed/27909995?tool=bestpractice.com[67]Viasus D, Ramos O, Ramos L, et al. Solithromycin for the treatment of community-acquired bacterial pneumonia. Expert Rev Respir Med. 2017;11:5-12.http://www.ncbi.nlm.nih.gov/pubmed/27753516?tool=bestpractice.com