接受非那雄胺治疗的患者中发生率为1.3%~1.8%。症状可在长期治疗过程中逐渐改善,停用该药后功能亦可恢复。[28]Kaufman KD, Olsen EA, Whiting D, et al. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J Am Acad Dermatol. 1998;39:578-589.http://www.ncbi.nlm.nih.gov/pubmed/9777765?tool=bestpractice.com[35]Drake L, Hordinsky M, Fiedler V, et al. The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia. J Am Acad Dermatol. 1999;41:550-554.http://www.ncbi.nlm.nih.gov/pubmed/10495374?tool=bestpractice.com虽然关于性功能相关副作用的质疑不断出现,目前已有的研究未能证实非那雄胺与性功能障碍的相关性。[29]Gupta AK, Charrette A. The efficacy and safety of 5α-reductase inhibitors in androgenetic alopecia: a network meta-analysis and benefit-risk assessment of finasteride and dutasteride. J Dermatolog Treat. 2014;25:156-161.http://informahealthcare.com/doi/pdf/10.3109/09546634.2013.813011http://www.ncbi.nlm.nih.gov/pubmed/23768246?tool=bestpractice.com
勃起功能障碍(ED)
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