毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔显著优于安慰剂。[23]Olsen EA, Whiting D, Bergfeld W, et al. A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2007;57:767-774.http://www.ncbi.nlm.nih.gov/pubmed/17761356?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔显著优于安慰剂。[23]Olsen EA, Whiting D, Bergfeld W, et al. A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2007;57:767-774.http://www.ncbi.nlm.nih.gov/pubmed/17761356?tool=bestpractice.com
毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔显著优于 2% 局部外用米诺地尔及安慰剂。[26]Olsen EA, Dunlap FE, Funicella T, et al. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2002;47:377-385.http://www.ncbi.nlm.nih.gov/pubmed/12196747?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔显著优于 2% 局部外用米诺地尔及安慰剂。[26]Olsen EA, Dunlap FE, Funicella T, et al. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2002;47:377-385.http://www.ncbi.nlm.nih.gov/pubmed/12196747?tool=bestpractice.com
毛发计数;脱发改善程度的主观评估;有中等质量的证据表明,在 24 个月的期间非那雄胺 1 mg/日,显著优于安慰剂。[19]Whiting DA, Olsen EA, Savin R, et al. Efficacy and tolerability of finasteride 1 mg in men aged 41 to 60 years with male pattern hair loss. Eur J Dermatol. 2003;13:150-160.http://www.ncbi.nlm.nih.gov/pubmed/12695131?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
毛发计数;脱发改善程度的主观评估;有中等质量的证据表明,在 24 个月的期间非那雄胺 1 mg/日,显著优于安慰剂。[19]Whiting DA, Olsen EA, Savin R, et al. Efficacy and tolerability of finasteride 1 mg in men aged 41 to 60 years with male pattern hair loss. Eur J Dermatol. 2003;13:150-160.http://www.ncbi.nlm.nih.gov/pubmed/12695131?tool=bestpractice.com
毛发计数;脱发改善程度的主观评估;有中等质量的证据表明,在超过 2 年的临床试验中,非那雄胺 1 mg/日,可延缓脱发进展、增加毛发生长。[28]Kaufman KD, Olsen EA, Whiting D, et al. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J Am Acad Dermatol. 1998;39:578-589.http://www.ncbi.nlm.nih.gov/pubmed/9777765?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
毛发计数;脱发改善程度的主观评估;有中等质量的证据表明,在超过 2 年的临床试验中,非那雄胺 1 mg/日,可延缓脱发进展、增加毛发生长。[28]Kaufman KD, Olsen EA, Whiting D, et al. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J Am Acad Dermatol. 1998;39:578-589.http://www.ncbi.nlm.nih.gov/pubmed/9777765?tool=bestpractice.com
毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔在女性型脱发的女性患者中显著优于安慰剂。[30]Lucky AW, Piacquadio DJ, Ditre CM, et al. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss. J Am Acad Dermatol. 2004;50:541-553.http://www.ncbi.nlm.nih.gov/pubmed/15034503?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
毛发计数;脱发改善程度的主观评估:有中等质量的证据表明,5% 局部外用米诺地尔在女性型脱发的女性患者中显著优于安慰剂。[30]Lucky AW, Piacquadio DJ, Ditre CM, et al. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss. J Am Acad Dermatol. 2004;50:541-553.http://www.ncbi.nlm.nih.gov/pubmed/15034503?tool=bestpractice.com