证据评分
鳞状细胞癌的发病率：中等质量证据表明日常应用防晒霜比随意应用或安慰剂对于减少鳞状细胞癌的发病率和新发日光性角化风险更有效果。[53]Lin JS, Eder M, Weinmann S. Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2011 Feb 1;154(3):190-201.http://www.ncbi.nlm.nih.gov/pubmed/21282699?tool=bestpractice.com[54]Green A, Williams G, Neale R, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinoma of the skin: a randomised controlled trial. Lancet. 1999 Aug 28;354(9180):723-9.http://www.ncbi.nlm.nih.gov/pubmed/10475183?tool=bestpractice.com[55]Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993 Oct 14;329(16):1147-51.https://www.nejm.org/doi/full/10.1056/NEJM199310143291602http://www.ncbi.nlm.nih.gov/pubmed/8377777?tool=bestpractice.com[56]Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003 Apr;139(4):451-5.https://jamanetwork.com/journals/jamadermatology/fullarticle/479276http://www.ncbi.nlm.nih.gov/pubmed/12707092?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
鳞状细胞癌的发病率：中等质量证据表明日常应用防晒霜比随意应用或安慰剂对于减少鳞状细胞癌的发病率和新发日光性角化风险更有效果。[53]Lin JS, Eder M, Weinmann S. Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2011 Feb 1;154(3):190-201.http://www.ncbi.nlm.nih.gov/pubmed/21282699?tool=bestpractice.com[54]Green A, Williams G, Neale R, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinoma of the skin: a randomised controlled trial. Lancet. 1999 Aug 28;354(9180):723-9.http://www.ncbi.nlm.nih.gov/pubmed/10475183?tool=bestpractice.com[55]Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993 Oct 14;329(16):1147-51.https://www.nejm.org/doi/full/10.1056/NEJM199310143291602http://www.ncbi.nlm.nih.gov/pubmed/8377777?tool=bestpractice.com[56]Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003 Apr;139(4):451-5.https://jamanetwork.com/journals/jamadermatology/fullarticle/479276http://www.ncbi.nlm.nih.gov/pubmed/12707092?tool=bestpractice.com
