如果眼压得到控制,一次急性闭角型青光眼的预后是令人满意的。42%-72%的患者眼压可以通过单纯的激光周边虹膜切开术得以控制,而且在白种人中的比例较亚洲人高。[47]Wishart PK, Atkinson PL. Extracapsular cataract extraction and posterior chamber lens implantation in patients with primary chronic angle-closure glaucoma: effect on intraocular pressure control. Eye. 1989;3:706-712.http://www.ncbi.nlm.nih.gov/pubmed/2630350?tool=bestpractice.com[49]Gunning FP, Greve EL. Lens extraction for uncontrolled glaucoma. J Cataract Refract Surg. 1998;24:1347-1356.http://www.ncbi.nlm.nih.gov/pubmed/9795850?tool=bestpractice.com
如果慢性闭角型青光眼患者的眼压控制的好,其渐进性视野缺损的过程也可得到控制。激光虹膜周边切开术的效果取决于确诊时的主要发病机制和青光眼的分期。[60]Ang LP, Aung T, Chua WH, et al. Visual field loss from primary angle-closure glaucoma: a comparative study of symptomatic and asymptomatic disease. Ophthalmology. 2004;111:1636-1640.http://www.ncbi.nlm.nih.gov/pubmed/15350315?tool=bestpractice.com
瞳孔前粘连的范围较大、眼压的持续升高、杯盘比大都是虹膜周切术后眼压控制不佳的预测指标。[61]Salmon JF. Long-term intraocular pressure control after Nd:YAG laser iridotomy in chronic angle-closure glaucoma. J Glaucoma. 1993;2:291-296.http://www.ncbi.nlm.nih.gov/pubmed/19920535?tool=bestpractice.com
一旦青光眼视神经病变逐渐加重,如出现视盘结构损害和/或视野缺损,94%-100%的患者都需要进一步治疗以控制眼压。[62]Rosman M, Aung T, Ang LP, et al. Chronic angle-closure with glaucomatous damage: longterm clinical course in a North American population and comparison with an Asian population. Ophthalmology. 2002;109:2227-2231.http://www.ncbi.nlm.nih.gov/pubmed/12466163?tool=bestpractice.com