使用行为治疗或者小组咨询的戒烟率:有高质量证据表明多次个人或小组咨询的行为支持可以帮助戒烟。[35]Stead LF, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database Syst Rev. 2005;(2):CD001007.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001007.pub2/fullhttp://www.ncbi.nlm.nih.gov/pubmed/15846610?tool=bestpractice.com[36]Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2005;(2):CD001292.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001292.pub2/fullhttp://www.ncbi.nlm.nih.gov/pubmed/15846616?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
使用行为治疗或者小组咨询的戒烟率:有高质量证据表明多次个人或小组咨询的行为支持可以帮助戒烟。[35]Stead LF, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database Syst Rev. 2005;(2):CD001007.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001007.pub2/fullhttp://www.ncbi.nlm.nih.gov/pubmed/15846610?tool=bestpractice.com[36]Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2005;(2):CD001292.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001292.pub2/fullhttp://www.ncbi.nlm.nih.gov/pubmed/15846616?tool=bestpractice.com
NRT的戒烟率:有高质量的证据表明,所有NRT有相似的效果,种类的选择应该基于预期的不良反应,患者喜好和可行性。[42]Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018 May 31;(5):CD000146.https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000146.pub5/fullhttp://www.ncbi.nlm.nih.gov/pubmed/29852054?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
NRT的戒烟率:有高质量的证据表明,所有NRT有相似的效果,种类的选择应该基于预期的不良反应,患者喜好和可行性。[42]Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018 May 31;(5):CD000146.https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000146.pub5/fullhttp://www.ncbi.nlm.nih.gov/pubmed/29852054?tool=bestpractice.com
联合NRT戒烟后6个月时的戒烟率:有高质量证据表明,与安慰剂相比,尼古丁贴剂和锭剂在戒烟后6个月时有较高的戒烟率。[43]Piper ME, Smith SS, Schlam TR, et al. A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies. Arch Gen Psychiatry. 2009 Nov;66(11):1253-62.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933113/http://www.ncbi.nlm.nih.gov/pubmed/19884613?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
联合NRT戒烟后6个月时的戒烟率:有高质量证据表明,与安慰剂相比,尼古丁贴剂和锭剂在戒烟后6个月时有较高的戒烟率。[43]Piper ME, Smith SS, Schlam TR, et al. A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies. Arch Gen Psychiatry. 2009 Nov;66(11):1253-62.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933113/http://www.ncbi.nlm.nih.gov/pubmed/19884613?tool=bestpractice.com
用NRT辅助的减量戒烟法的持续戒烟效果:有高质量证据表明,对于没有意愿戒烟或不能突然戒烟的吸烟者来讲,与安慰剂相比,NRT是一个有效的方法可达到稳定的戒烟效果。[52]Moore D, Aveyard P, Connock M, et al. Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis. BMJ. 2009 Apr 2;338:b1024.http://www.bmj.com/cgi/content/full/338/apr02_3/b1024http://www.ncbi.nlm.nih.gov/pubmed/19342408?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
用NRT辅助的减量戒烟法的持续戒烟效果:有高质量证据表明,对于没有意愿戒烟或不能突然戒烟的吸烟者来讲,与安慰剂相比,NRT是一个有效的方法可达到稳定的戒烟效果。[52]Moore D, Aveyard P, Connock M, et al. Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis. BMJ. 2009 Apr 2;338:b1024.http://www.bmj.com/cgi/content/full/338/apr02_3/b1024http://www.ncbi.nlm.nih.gov/pubmed/19342408?tool=bestpractice.com
基于网络或计算机的戒烟项目的戒烟率:有高质量的证据显示,基于网络或计算机的戒烟项目(单独或与其他干预方式联用),在成年吸烟者戒烟有显著效果。[65]Myung SK, McDonnell DD, Kazinets G, et al. Effects of web- and computer-based smoking cessation programs: meta-analysis of randomized controlled trials. Arch Intern Med. 2009 May 25;169(10):929-37. [Erratum in: Arch Intern Med. 2009 Jul 13;169(13):1194.]https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/773520http://www.ncbi.nlm.nih.gov/pubmed/19468084?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
基于网络或计算机的戒烟项目的戒烟率:有高质量的证据显示,基于网络或计算机的戒烟项目(单独或与其他干预方式联用),在成年吸烟者戒烟有显著效果。[65]Myung SK, McDonnell DD, Kazinets G, et al. Effects of web- and computer-based smoking cessation programs: meta-analysis of randomized controlled trials. Arch Intern Med. 2009 May 25;169(10):929-37. [Erratum in: Arch Intern Med. 2009 Jul 13;169(13):1194.]https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/773520http://www.ncbi.nlm.nih.gov/pubmed/19468084?tool=bestpractice.com
尼古丁疫苗的戒烟率:有高质量证据提示,当可以达到足够高的抗体水平时,尼古丁-Q-β疫苗可显著提高吸烟者的持续戒烟率。[72]Cornuz J, Zwahlen S, Jungi WF, et al. A vaccine against nicotine for smoking cessation: a randomized controlled trial. PLoS One. 2008;3:e2547.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432028/?tool=pubmedhttp://www.ncbi.nlm.nih.gov/pubmed/18575629?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
尼古丁疫苗的戒烟率:有高质量证据提示,当可以达到足够高的抗体水平时,尼古丁-Q-β疫苗可显著提高吸烟者的持续戒烟率。[72]Cornuz J, Zwahlen S, Jungi WF, et al. A vaccine against nicotine for smoking cessation: a randomized controlled trial. PLoS One. 2008;3:e2547.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432028/?tool=pubmedhttp://www.ncbi.nlm.nih.gov/pubmed/18575629?tool=bestpractice.com
戒烟贴剂和其他形式的NRT联用的戒烟率:中等质量的证据表明,在尼古丁贴剂的基础上增加其他形式的NRT可以增加成功率。[42]Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018 May 31;(5):CD000146.https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000146.pub5/fullhttp://www.ncbi.nlm.nih.gov/pubmed/29852054?tool=bestpractice.com
系统评价或者受试者>200名的随机对照临床试验(RCT)。
戒烟贴剂和其他形式的NRT联用的戒烟率:中等质量的证据表明,在尼古丁贴剂的基础上增加其他形式的NRT可以增加成功率。[42]Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018 May 31;(5):CD000146.https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000146.pub5/fullhttp://www.ncbi.nlm.nih.gov/pubmed/29852054?tool=bestpractice.com