证据评分
黑棘皮病的皮损清除及复发：目前没有充足的证据证明激光治疗可以完全清除皮损且2年内没有复发。[35]Bredlich RO, Krahn G, Kunzi-Rapp K, et al. Continuous-wave carbon dioxide laser therapy in pseudoacanthosis nigricans. Br J Dermatol. 1998 Nov;139(5):937-8.http://www.ncbi.nlm.nih.gov/pubmed/9892981?tool=bestpractice.com[36]Rosenbach A, Ram R. Treatment of Acanthosis nigricans of the axillae using a long-pulsed (5-msec) alexandrite laser. Dermatol Surg. 2004 Aug;30(8):1158-60.http://www.ncbi.nlm.nih.gov/pubmed/15274711?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
黑棘皮病的皮损清除及复发：目前没有充足的证据证明激光治疗可以完全清除皮损且2年内没有复发。[35]Bredlich RO, Krahn G, Kunzi-Rapp K, et al. Continuous-wave carbon dioxide laser therapy in pseudoacanthosis nigricans. Br J Dermatol. 1998 Nov;139(5):937-8.http://www.ncbi.nlm.nih.gov/pubmed/9892981?tool=bestpractice.com[36]Rosenbach A, Ram R. Treatment of Acanthosis nigricans of the axillae using a long-pulsed (5-msec) alexandrite laser. Dermatol Surg. 2004 Aug;30(8):1158-60.http://www.ncbi.nlm.nih.gov/pubmed/15274711?tool=bestpractice.com
