BMJ Best Practice
最后审核时间: 七月 2019
最近更新时间: 五月 2019

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 不适感
  • 发热
  • 腹泻

其他诊断因素

  • 新生儿:肝脾肿大
  • 新生儿:瘀点或瘀斑
  • 疼痛和四肢无力

危险因素

  • 巨细胞病毒(CMV)D + / R -状态(供体CMV阳性、受体阴性)的实体器官移植接受者
  • CMV R +移植接受者
  • 免疫抑制药物的类型
  • 艾滋病 (AIDS)

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 血清肌酐
  • 血清天门冬氨酸氨基转移酶 (AST) 和丙氨酸氨基转移酶 (ALT)
  • 血清碱性磷酸酶
全部具体信息

需要考虑的检查

  • 胸部 CT 扫描
  • 活组织检查样本病理学检查
  • 上消化道内镜及结肠镜检查
  • 系列胎儿超声检查(先天性巨细胞病毒感染)
全部具体信息

治疗流程

贡献者

Infectious Disease Service and Transplantation Center

University Hospital (CHUV)

University of Lausanne

Lausanne

Switzerland

利益冲突披露
MM declares that he has no competing interests.

Infectious Disease Service and Transplantation Center

University Hospital (CHUV)

University of Lausanne

Lausanne

Switzerland

利益冲突披露
OM has received research grants from Lophius

Dr Matteo Mombelli and Dr Oriol Manuel would like to thank Dr Sandra Asner from the University Hospital of Lausanne, Switzerland for her careful review of congenital CMV in this topic. They would also like to gratefully acknowledge Dr Raymund R. Razonable and Dr Atul Humar, the previous contributors to this topic.

利益冲突披露
RRR is an author of a number of references cited in this topic. AH has done consultancy work for Astellas, Chimerix, and Roche.

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Assistant Professor

Department of Family Medicine

University of Maryland School of Medicine

MD

利益冲突披露
GHT declares that he has no competing interests.

Clinical Director

HIV and Sexual Health

Chelsea and Westminster Hospital

London

UK

利益冲突披露
SB has been funded by GlaxoSmithKline and Gilead for speaking at scientific meetings.

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