TOF 修复术后的患者应接受儿科心脏病医生的常规评估。 美国心脏病学会和美国心脏协会的联合指南建议,TOF 修复术后的成年患者应至少每年进行一次随访,随访的心内科医生应具备成人先天性心脏病 (CHD) 的专业知识。 指南还建议,对这些成年患者进行超声心动图检查和/或 MRI,检查人员应具备成年人 CHD 的专业知识。[41]Warnes CA, Williams RG, Bashore TM, et al. ACC/AHA 2008 guidelines for the management of adults with congenital heart disease. Circulation. 2008 Dec 2;118(23):e714-833.http://circ.ahajournals.org/content/118/23/e714.fullhttp://www.ncbi.nlm.nih.gov/pubmed/18997169?tool=bestpractice.com 欧洲心脏病学会指南还建议,TOF 成年患者也应由先天性心脏病的专科医生进行随访。[42]Baumgartner H, Bonhoeffer P, De Groot NM, et al. ESC guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J. 2010 Dec;31(23):2915-57.https://academic.oup.com/eurheartj/article/31/23/2915/2398053http://www.ncbi.nlm.nih.gov/pubmed/20801927?tool=bestpractice.com
对于患有 TOF 但已修复的女性而言,受孕前咨询和妊娠期管理尤为重要。[43]Canobbio MM, Warnes CA, Aboulhosn J, et al; American Heart Association. Management of pregnancy in patients with complex congenital heart disease: a scientific statement for healthcare professionals from the American Heart Association. Circulation. 2017 Feb 21;135(8):e50-87.http://circ.ahajournals.org/content/135/8/e50.longhttp://www.ncbi.nlm.nih.gov/pubmed/28082385?tool=bestpractice.com
应每 1 至 5 年做一次超声心动图,评估右心室 (RV) 功能及肺动脉瓣狭窄或关闭不全的进展。 时间根据患者而定,出现显著进行性RV 扩张、肺动脉瓣狭窄或关闭不全以及其他症状的患者,每年至少应接受一次扫描。
心脏 MRI 或 CT 是用于评估右心室体积和功能的附加手段,应用地越来越多。[44]American College of Radiology. ACR Appropriateness Criteria® known or suspected congenital heart disease in the adult. Jun 2016 [internet publication].https://acsearch.acr.org/docs/69355/Narrative/ MRI 能准确测量RV的三维容积测量,越来越广泛地被用于确定肺动脉瓣置换术的时间。[42]Baumgartner H, Bonhoeffer P, De Groot NM, et al. ESC guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J. 2010 Dec;31(23):2915-57.https://academic.oup.com/eurheartj/article/31/23/2915/2398053http://www.ncbi.nlm.nih.gov/pubmed/20801927?tool=bestpractice.com[45]Valente AM, Cook S, Festa P, et al. Multimodality imaging guidelines for patients with repaired tetralogy of Fallot: a report from the American Society of Echocardiography: developed in collaboration with the Society for Cardiovascular Magnetic Resonance and the Society for Pediatric Radiology. J Am Soc Echocardiogr. 2014 Feb;27(2):111-41.http://www.ncbi.nlm.nih.gov/pubmed/24468055?tool=bestpractice.com 经常需要在先天性心脏病专科医师的指导下,根据患者的具体问题,考虑使用多模式影像学检查方案。[45]Valente AM, Cook S, Festa P, et al. Multimodality imaging guidelines for patients with repaired tetralogy of Fallot: a report from the American Society of Echocardiography: developed in collaboration with the Society for Cardiovascular Magnetic Resonance and the Society for Pediatric Radiology. J Am Soc Echocardiogr. 2014 Feb;27(2):111-41.http://www.ncbi.nlm.nih.gov/pubmed/24468055?tool=bestpractice.com