早发型肌张力障碍患病率人群研究的估计值差异非常大，最低为 7/100,000，最高为 500/100,000。[2]Tarsy D, Simon DK. Dystonia. N Engl J Med. 2006 Aug 24;355(8):818-29.http://www.ncbi.nlm.nih.gov/pubmed/16928997?tool=bestpractice.com[3]Defazio G, Abbruzzese G, Livrea P, et al. Epidemiology of primary dystonia. Lancet Neurol. 2004 Nov;3(11):673-8.http://www.ncbi.nlm.nih.gov/pubmed/15488460?tool=bestpractice.com[4]Liu X, Luo X, Hu W. Studies on the epidemiology and etiology of moldy sugarcane poisoning in China. Biomed Environ Sci. 1992 Jun;5(2):161-77.http://www.ncbi.nlm.nih.gov/pubmed/1642790?tool=bestpractice.com[5]Muller J, Kiechl S, Wenning GK, et al. The prevalence of primary dystonia in the general community. Neurology. 2002 Sep 24;59(6):941-3.http://www.ncbi.nlm.nih.gov/pubmed/12297587?tool=bestpractice.com 1998 年，在美国明尼苏达州罗切斯特市进行的一项流行病学研究估计，在美国约有 88,000 名原发性局灶性肌张力障碍患者，由此计算得出的患病率为 33/100,000，但是由于存在未确诊的病例，该数值很可能有所低估。[6]Nutt JG, Muenter MD, Aronson A, et al. Epidemiology of focal and generalized dystonia in Rochester, Minnesota. Mov Disord. 1988;3(3):188-94.http://www.ncbi.nlm.nih.gov/pubmed/3264051?tool=bestpractice.com
特定亚群的患病率更高，如德系犹太人的患病率估计值高达 1110/100,000。 如果将晚发型病例包括在内，则肌张力障碍的患病率估计值为 300/100,000 至 732/100,000。[3]Defazio G, Abbruzzese G, Livrea P, et al. Epidemiology of primary dystonia. Lancet Neurol. 2004 Nov;3(11):673-8.http://www.ncbi.nlm.nih.gov/pubmed/15488460?tool=bestpractice.com[4]Liu X, Luo X, Hu W. Studies on the epidemiology and etiology of moldy sugarcane poisoning in China. Biomed Environ Sci. 1992 Jun;5(2):161-77.http://www.ncbi.nlm.nih.gov/pubmed/1642790?tool=bestpractice.com[7]Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group. A prevalence study of primary dystonia in eight European countries. J Neurol. 2000 Oct;247(10):787-92.http://www.ncbi.nlm.nih.gov/pubmed/11127535?tool=bestpractice.com
