成人阻塞型睡眠呼吸暂停

呼气正压装置（EPAP）

provent（商品名）是一次性鼻呼气压力阀，夜间放入鼻孔。研究表明这种装置可以使平均AHI为14-17的患者AHI下降平均达50%-70%，和对照相比，可以改善主观睡眠和客观睡眠质量。[174]Rosenthal L, Massie CA, Dolan DC, et al. A multicenter, prospective study of a novel nasal EPAP device in the treatment of obstructive sleep apnea: efficacy and 30-day adherence. J Clin Sleep Med. 2009;5:532-537.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792968/?tool=pubmedhttp://www.ncbi.nlm.nih.gov/pubmed/20465019?tool=bestpractice.com[175]Berry RB, Kryger MH, Massie CA. A novel nasal expiratory positive airway pressure (EPAP) device for the treatment of obstructive sleep apnea: a randomized controlled trial. Sleep. 2011;34:479-485.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065258/http://www.ncbi.nlm.nih.gov/pubmed/21461326?tool=bestpractice.com[176]Kryger MH, Berry RB, Massie CA. Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA). J Clin Sleep Med. 2011;7:449-453B.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190843/http://www.ncbi.nlm.nih.gov/pubmed/22003339?tool=bestpractice.com它并没有明显改变睡眠结构。能接受该装置和使用装置有效的患者选择标准还不清楚。这个装置可以在气道横截面积最小的时候象支架一样撑开气道。需要入选更多严重呼吸暂停患者的大型研究来评估其有效性和长期的依从性。