血管性痴呆

银杏

在治疗痴呆方面，银杏似乎比安慰剂治疗老年痴呆症更有效，然而，其临床相关性难以确定。[48]Kasper S, Schubert H. Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability [in German]. Fortschr Neurol Psychiatr. 2009;77:494-506.http://www.ncbi.nlm.nih.gov/pubmed/19621278?tool=bestpractice.com[49]Weinmann S, Roll S, Schwarzbach C, et al. Effects of ginkgo biloba in dementia: systematic review and meta-analysis. BMC Geriatr. 2010;10:14.https://bmcgeriatr.biomedcentral.com/articles/10.1186/1471-2318-10-14http://www.ncbi.nlm.nih.gov/pubmed/20236541?tool=bestpractice.com证据 A延缓症状进展：有来自系统评价的优质证据表明，银杏制剂在延缓症状进展方面效果有限。[48]Kasper S, Schubert H. Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability [in German]. Fortschr Neurol Psychiatr. 2009;77:494-506.http://www.ncbi.nlm.nih.gov/pubmed/19621278?tool=bestpractice.com系统评价或者受试者＞200名的随机对照临床试验（RCT）。

脑蛋白水解物

脑活素作为血管性痴呆的一种潜在治疗似乎具有前景，[50]Guekht AB, Moessler H, Novak PH, et al. Cerebrolysin in vascular dementia: improvement of clinical outcome in a randomized, double-blind, placebo-controlled multicenter trial. J Stroke Cerebrovasc Dis. 2011;20:310-318.http://www.ncbi.nlm.nih.gov/pubmed/20656516?tool=bestpractice.com 但还需进一步的试验来证实其益处。 [ ]In people with vascular dementia, does cerebrolysin improve outcomes compared with placebo?https://cochranelibrary.com/cca/doi/10.1002/cca.130/full显示答案 一项 Cochrane 综述发现，脑蛋白水解物可能会对认知功能和整体功能产生积极效果，但目前仍没有足够的证据推荐其作为血管性痴呆患者的一种常规疗法。[51]Chen N, Yang M, Guo J, et al. Cerebrolysin for vascular dementia. Cochrane Database Syst Rev. 2013;(1):CD008900.http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008900.pub2/fullhttp://www.ncbi.nlm.nih.gov/pubmed/23440834?tool=bestpractice.com