证据
- What are the effects of maintenance treatment with antipsychotic drugs in people with schizophrenia?
- How do antipsychotic combinations compare with antipsychotic monotherapy for people with schizophrenia?
- In people with schizophrenia, what are the effects of perphenazine?
- How does haloperidol compare with first generation antipsychotics for improving outcomes in adults with schizophrenia?
- How does fluphenazine deconoate compare with other neuroleptics in people with schizophrenia?
- In people with schizophrenia, is there randomized controlled trial evidence to support the use of psychoeducation?
- How does cognitive behavioral therapy compare with other psychosocial treatments for schizophrenia?
- In people with chronic mental illnesses, how do life skills programs affect outcomes?
- What are the effects of music therapy in people with schizophrenia and schizophrenia-like disorders?
- In people with psychosis-induced aggression or agitation, how does droperidol compare with placebo and other treatments in improving outcomes?
- What are the benefits and harms of aripiprazole compared with other atypical antipsychotics in people with schizophrenia?
证据评分
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证据 A
住院率、治疗依从性及社会功能：有高质量证据表明，对于患有严重精神疾病的患者，强调少数病例（少于 20）及高强度投入的强化个案管理 (intensive case management, ICM)项目减少了入院率、提高患者依从性、改善患者社会功能。[160]
证据 B烟草使用减少及戒烟：有中等质量证据表明对于患有精神分裂症吸烟者，安非他酮可能能够减少其烟草使用量并提高禁戒率，并不影响患者症状的稳定性。[221]
证据 C复发事件及住院治疗：有低质量证据表明，家庭干预措施（用于减少家庭成员间情绪爆发水平的社会心理干预措施的一种形式），可能能够减少精神分裂症患者的复发频率及住院率。[172]
证据 C药物治疗耐受患者的临床症状改善：有低质量证据表明在对其他抗精神病药物（包括氯氮平）耐受的患者中，舒必利加氯氮平联合用药比氯氮平单药治疗更为有效的改善临床症状。[197]
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