重症联合免疫缺陷

SCID 的诊断标准通常包括下述内容：[6]Al-Herz W, Bousfiha A, Casanova JL, et al. Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. Front Immunol. 2014;5:162.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001072/http://www.ncbi.nlm.nih.gov/pubmed/24795713?tool=bestpractice.com[37]Shearer WT, Dunn E, Notarangelo LD, et al. Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: the Primary Immune Deficiency Treatment Consortium experience. J Allergy Clin Immunol. 2014;133:1092-1098.http://www.ncbi.nlm.nih.gov/pubmed/24290292?tool=bestpractice.com

• 无T细胞或T细胞显著缺陷伴T细胞功能不良（主要标准）

• 抗体缺陷

• 分子缺陷对于诊断不具必要性。