建议对有潜在恶性转化风险的AK每6个月至12个月监测一次,观察是否进展为原位鳞状细胞癌(SCC)(鲍温病)或侵袭性SCC。[75]European Dermatology Forum. Evidence and consensus based (S3) guidelines for the treatment of actinic keratosis. 2015. http://www.euroderm.org (last accessed 26 September 2016).http://www.euroderm.org/edf/index.php/edf-guidelines/category/5-guidelines-miscellaneous
对一些高危患者,如免疫抑制、器官移植的患者、着色性干皮和白化病患者以及存在高风险因素的患者(如户外工作者、体育运动员、浅肤色人群、中年以上男性)应该保证更频繁的监测。[47]de Berker D, McGregor JM, Hughes BR; British Association of Dermatologists
Therapy Guidelines and Audit Subcommittee. Guidelines for the management of actinic keratoses. Br J Dermatol. 2007;156:222-230.http://www.bad.org.uk/library-media%5Cdocuments%5CActinic_keratoses_guidelines_2007.pdfhttp://www.ncbi.nlm.nih.gov/pubmed/17223860?tool=bestpractice.com