新型抗真菌药物
一些病例报道和动物实验建议泊沙康唑和伏立康唑治疗组织胞浆菌感染有效，然而目前仍然缺乏足够的数据。[48]Wheat LJ, Connolly P, Smedema M, et al. Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole. J Antimicrob Chemother. 2006;57:1235-1239.http://jac.oxfordjournals.org/content/57/6/1235.fullhttp://www.ncbi.nlm.nih.gov/pubmed/16627592?tool=bestpractice.com艾沙康唑鎓 (Isavuconazonium)（艾沙康唑的前体药物）是一种广谱三唑类抗真菌药物，对荚膜组织胞浆菌有活性。[49]Seyedmousavi S, Verweij PE, Mouton JW. Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases. Expert Rev Anti Infect Ther. 2015;13:9-27.http://www.ncbi.nlm.nih.gov/pubmed/25488140?tool=bestpractice.com
皮质类固醇
有报道称在发生呼吸困难，低氧血症或呼吸窘迫的患者中，早期（2周内)联合使用甲泼尼松龙和抗真菌药物可以改善临床症状，然而目前仍然缺乏相关临床试验支持该建议。[50]Kataria YP, Campbell PB, Burlingham BT. Acute pulmonary histoplasmosis presenting as adult respiratory distress syndrome: effect of therapy on clinical and laboratory features. South Med J. 1981;74:534-537, 542.http://www.ncbi.nlm.nih.gov/pubmed/7244706?tool=bestpractice.com
